- Renal dysfunction associated with the administration of high-dose interleukin-2 in 199 consecutive patients with metastatic melanoma or renal carcinoma. Guleria, A.S., Yang, J.C., Topalian, S.L., Weber, J.S., Parkinson, D.R., MacFarlane, M.P., White, R.L., Steinberg, S.M., White, D.E., Einhorn, J.H. J. Clin. Oncol. (1994)