Disease relevance of Oliguria

• In the other four rabbits, development of 2KGH was accompanied by increased PRA, increased IPGE, and decreased RBF and GFR, and indomethacin produced renal failure, oliguria, malignant hypertension, and death within 5 days [1].
• Hypotension with oliguria: a side-effect of azathioprine [2].
• Poor prognostic indicators included oliguria, urine sediment abnormalities and, most importantly, severity of renal insufficiency; with an increase in serum creatinine of 3 mg/dl or greater, the mortality rate was 64 percent [3].
• Blood urea nitrogen and creatinine rose dramatically, in the setting of oliguria or anuria [4].
• CONCLUSIONS: Renin gene expression persists and predominates in the deep renal cortex of the stillborn IUGR fetus, and could contribute to the pathogenesis of neonatal oliguria and/or hypertension during postnatal life [5].

High impact information on Oliguria

• Oliguria occurred in 5 infants treated with ibuprofen and in 14 treated with indomethacin (P=0.03) [6].
• The frequencies of ARF (27/65 [42%] vs 15/64 [23%], p=0.028) and oliguria (35/62 [56%] vs 23/63 [37%], p=0.025) and the peak serum creatinine concentration (225 [130-339] vs 169 [106-273] micromol/L, p=0.04) were significantly higher in the hydroxyethylstarch group than in the gelatin group [7].
• 3. ACS occurs in 15% of patients and is characterized by high peak inspiratory pressure, CO2 retention, and oliguria [8].
• Use of automated biochemical monitoring, aminoglycoside antibiotic utilization, and administration of potent diuretics and mannitol in settings of oliguria all contribute to its increased incidence [9].
• The incidence of postransplant renal failure was the same in both groups (16%), but the duration of oliguria was lower in group A than in group B (3.3 +/- 2 vs. 16.2 +/- 10.7 days, P less than 0.05), as well as the incidence of acute rejection during the first 3 months (18% vs. 40%, P = 0.01 [10].

Chemical compound and disease context of Oliguria

• Dopamine and saralasin antagonism of renal vasoconstriction and oliguria caused by amphotericin B in dogs [11].
• In these 15 patients, low-dose dopamine infusion produced significant improvement in renal function, with resolution of oliguria in every case, and with no deleterious hemodynamic effect [12].
• Oliguria: fluid deprivation or furosemide deficiency [13]?
• Excessive antidiuretic hormone secretion is common after radical cystectomy and should be considered in the differential diagnosis of postoperative oliguria in these patients [14].
• During the next three years, of 912 patients given two to three days gentamicin, 29 patients were shown to have potentially toxic serum levels and oliguria [15].

Biological context of Oliguria

• All nine AZA and 18 of the 27 CSA patients with prolonged oliguria subsequently had a spontaneous diuresis [16].
• Despite volume loading, animals demonstrate a fall in glomerular filtration rate, oliguria, low fractional sodium excretion, maintained urine osmolarity, and increased plasma renin activity [17].
• OBJECTIVE: To assess the effect of low dose dopamine on the urine output in postpartum pre-eclamptic or eclamptic women with oliguria [18].
• The oliguria in the DI rats could not have been due to a release of antidiuretic hormone, and was attributed to the diminished water intake in both strains [19].
• CONCLUSION: Caval replacement after circumferential resection of the inferior vena cava may be necessary in patients who have preoperative poor development of collateral circulation or who have oliguria or unstable hemodynamics intraoperatively [20].

Anatomical context of Oliguria

• In a child with renal failure and oliguria due to hyperoxaluria myelophthisis developed as a result of extensive bone-marrow replacement with calcium oxalate crystals and an accompanying fibrous proliferations [21].
• The new score included seven variables: cyanosis (2 points), Glasgow coma scale less than 8 (2 points), refractory hypotension (2 points), oliguria (1 point), leukocytes less than 4000/mm(3) (1 point), partial thromboplastin time more than 150% of control value (1 point) and base deficit more than 10 mmol/l (1 point) [22].
• These findings, coupled with observed increases in urinary glucose levels and consistent specific gravity readings of 1.01 even though treated rats were experiencing oliguria, provide evidence for OOS-Me-induced kidney tubule damage [23].
• Interstitial fluid retention and oliguria (baseline, 1.7 ml/kg per hour; nadir, 0.5 mg/kg per hour) were associated with hypotension (baseline, 101/56 mm Hg; nadir, 85/43 mm Hg) and decreased intravascular volume (plasma renin activity increased x 10) [24].
• Acute oliguria in preterm infants with hyaline membrane disease: interaction of dopamine and furosemide [25].

Gene context of Oliguria

• Plasma CSA levels fluctuated widely in all patients, but were not higher in any group, including those with prolonged oliguria [16].
• MEASUREMENTS AND MAIN RESULTS: Urine output was monitored hourly before and after dopamine was instituted for the treatment of oliguria [26].
• (2) Fifteen infants had transient oliguria (beta 2-microglobulin level was elevated in eight infants) [27].
• All six patients belonging to the third group (oliguria for more than 14 days or anuria for more than 7 days) had late sequelae: two started haemodialysis more than 10 years after the initial phase; three have a decreased GFR and concentrating capacity [28].
• After the operation, the pressure in the inferior vena cava increased, leading to oliguria and ascites [29].

Analytical, diagnostic and therapeutic context of Oliguria

• Hemodialysis was performed because of oliguria and a rising serum creatinine value [30].
• Criteria for admission to the study were oliguria or increasing serum creatinine in the first 12 hr after renal transplantation [31].
• Dopamine was given at a dose of 6.1 +/- 3.0 microgram/kg per minute to combat oliguria, impaired peripheral perfusion, or both [32].
• Postoperative oliguria occurred in two of the ten patients in the control group and in three of the 13 given dopamine (P = 0.74) [33].
• To determine the mechanism by which oliguria develops during raised intra-abdominal pressure secondary to CO2 insufflation, we created a rat pneumoperitoneum model [34].

References