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CC chemokines in allergic inflammation.

CC chemokines are small inducible proteins that are related to interleukin 8. Recent studies have shown that several CC chemokines, MCP-1, MCP-3, RANTES and MIP-1 alpha, act on basophils and/or eosinophils via GTP-binding protein-coupled receptors. Marco Baggiolini and Clemens Dahinden discuss the involvement of CC chemokines in the recruitment and activation of the main effector cells of allergic inflammation.[1]


  1. CC chemokines in allergic inflammation. Baggiolini, M., Dahinden, C.A. Immunol. Today (1994) [Pubmed]
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