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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Radioallergosorbent and indirect fluorescent antibody tests in immunodiagnosis of schistosomiasis.

Radioallergosorbent tests for specific IgE antibodies to Schistosoma haematobium and S. mansoni were positive in 82 and 72%, respectively, of sera from 136 African schistosomiasis patients. 99% of sera from controls (5 free of parasitic disease, 75 infested with hookworm, Ascaris, Trichuris, and/or Onchocerca) were negative. When titres in indirect fluorescent antibody tests were set at the same level of specificity only 38% of patients' sera were positive. A cut-off at a higher concentration increased sensitivity to 65% but lowered specificity (10% controls positive).[1]

References

  1. Radioallergosorbent and indirect fluorescent antibody tests in immunodiagnosis of schistosomiasis. Weiss, N., Stürchler, D., Dietrich, F.M. Lancet (1978) [Pubmed]
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