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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Prostaglandin prophylaxis and bladder function after vaginal hysterectomy: a prospective randomised study.

OBJECTIVE: To assess the efficacy of prostaglandins in enhancing bladder function after vaginal hysterectomy. DESIGN: Prospective randomised study of women who underwent vaginal hysterectomy between November 1989 and August 1990. SETTING: Sackler School of Medicine Tel Aviv University Medical Center, Department of Obstetrics and Gynaecology 'B'. SUBJECTS: 24 women who underwent vaginal hysterectomy and anterior and posterior colporrhaphy for prolapse. INTERVENTION: Administration of prostaglandin F2 alpha 5 mg intravesically or E2 3 mg intravaginally versus 100 ml saline intravesically (control) daily, starting on the first postoperative day, until adequate spontaneous voiding was established. RESULTS: Women receiving PGE2 resumed spontaneous bladder functions earlier, required significantly fewer days catheterisation and had significantly less febrile morbidity compared to women in the control group or PGE2 group. CONCLUSIONS: Prostaglandins PGE2 intravaginally are beneficial in enhancing functions after vaginal hysterectomy [corrected].[1]

References

  1. Prostaglandin prophylaxis and bladder function after vaginal hysterectomy: a prospective randomised study. Bergman, A., Mushket, Y., Gordon, D., David, M.P. British journal of obstetrics and gynaecology. (1993) [Pubmed]
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