Your search matched a total of 1038 documents. Results 1 - 10.
Homo sapiens
Gene: ... with a sensitivity of 70 %, 79 %, 89 %, and 75 %, respectively, with 100% specificity for all of the genes....Disease relevance of APC Germ- line mutations in the adenomatous polyposis coli( APC) gene...- line defects: mutation of the APC gene or mutation of a mismatch- repair gene. In turn, expression... / Synonyms: Protein APC
MeSH term: ... Disease relevance of Genes, APC Familial adenomatous polyposis is an autosomal dominant disease caused by a germ- line mutation of the adenomatous polyposis coli( APC) gene that causes colorectal... polyposis coli gene( APC) cause the appearance of large numbers of colon polyps, the familial polyposis... / Synonyms: APC Gene; APC Genes; Gene, APC
Mus musculus
Gene: ... of Apc gene disruption, all of which are on exon 15. The protein product, adenomatous polyposis coli( APC...Disease relevance of Apc Furthermore, treating Apc delta716 mice with a novel COX- 2 inhibitor.... Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2( COX- 2... / Synonyms: Protein APC; mAPC
Drosophila melanogaster
Gene: ... Disease relevance of Apc Mutations in the adenomatous polyposis coli gene( which encodes a protein called APC) are associated with the formation of intestinal polyps and colon cancers. Inactivation of the Adenomatous Polyposis Coli( APC) tumor suppressor triggers the development of most colorectal carcinomas... / Synonyms: APC; APC1; Apc1
Rattus norvegicus
Gene: ... Disease relevance of Apc Thus, APNH induced liver and colon cancers with K- ras, beta- catenin and Apc gene mutations in F344 rats. Loss of functional adenomatous polyposis coli protein( APC) leads.... These results suggest that the APC- beta- catenin- T- cell factor signaling pathway is involved... / Synonyms: Protein APC
Drosophila melanogaster
Gene: ... colocalization with actin in many but not all cellular contexts, and also suggested a possible interaction...Disease relevance of Apc2 For example, dAPC2 has a striking asymmetric distribution in neuroblasts, and dAPC2 colocalizes with assembling actin filaments at the base of developing larval denticles... / Synonyms: APC; APC2; D-APC2
Homo sapiens
Gene: ... High impact information on APC2 Like APC, APC2 regulates the formation of active betacatenin- Tcf complexes, as demonstrated using transient transcriptional activation assays in APC -/- colon carcinoma cells. Tumour cell lines stably transfected with LEF1( DN) or APC2, or transiently transfected... / Synonyms: APC-like
Pan troglodytes
Gene: ... High impact information on APC More importantly, they show that the s. c. route of injection delivers these APC to sites of T cell activation, a prerequisite for the generation of an effective immune... APC....
Danio rerio
Gene: ... High impact information on apc In contrast, treatment of apc mutants with all- trans retinoic acid rescued retinal differentiation defects but had no apparent effect on the lens. These observations establish apc- mutant zebrafish as a bona fide model for the study of digestive tract cancer....
MeSH term: ... and activated protein C resistance. This phenomenon, designated as acquired APC resistance, is more pronounced... of normal FV, FV( Leiden ), or FV( R2) were assayed with an APC resistance assay that specifically measures the APC cofactor activity of FV in FVIIIa inactivation, and with the activated partial thromboplastin time... / Synonyms: APC Resistance; Resistance, APC
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Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
