Gene Review:
Apc - APC-like
Drosophila melanogaster
Synonyms:
APC, APC1, Apc1, CG1451, D-APC, ...
- A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates beta-catenin but its zygotic expression is not essential for the regulation of Armadillo. Hayashi, S., Rubinfeld, B., Souza, B., Polakis, P., Wieschaus, E., Levine, A.J. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Drosophila Apc1 and Apc2 regulate Wingless transduction throughout development. Ahmed, Y., Nouri, A., Wieschaus, E. Development (2002)
- A Drosophila APC tumour suppressor homologue functions in cellular adhesion. Hamada, F., Bienz, M. Nat. Cell Biol. (2002)
- Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development. Ahmed, Y., Hayashi, S., Levine, A., Wieschaus, E. Cell (1998)
- Independent regulation of synaptic size and activity by the anaphase-promoting complex. van Roessel, P., Elliott, D.A., Robinson, I.M., Prokop, A., Brand, A.H. Cell (2004)
- The APC tumour suppressor has a nuclear export function. Rosin-Arbesfeld, R., Townsley, F., Bienz, M. Nature (2000)
- Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein. Matsumine, A., Ogai, A., Senda, T., Okumura, N., Satoh, K., Baeg, G.H., Kawahara, T., Kobayashi, S., Okada, M., Toyoshima, K., Akiyama, T. Science (1996)
- The dominant mutation Glazed is a gain-of-function allele of wingless that, similar to loss of APC, interferes with normal eye development. Brunner, E., Brunner, D., Fu, W., Hafen, E., Basler, K. Dev. Biol. (1999)
- Identification and characterization of E-APC, a novel Drosophila homologue of the tumour suppressor APC. Hamada, F., Murata, Y., Nishida, A., Fujita, F., Tomoyasu, Y., Nakamura, M., Toyoshima, K., Tabata, T., Ueno, N., Akiyama, T. Genes Cells (1999)
- Actin-dependent membrane association of a Drosophila epithelial APC protein and its effect on junctional Armadillo. Townsley, F.M., Bienz, M. Curr. Biol. (2000)
- Drosophila APC2 and APC1 have overlapping roles in the larval brain despite their distinct intracellular localizations. Akong, K., McCartney, B.M., Peifer, M. Dev. Biol. (2002)
- Shortstop recruits EB1/APC1 and promotes microtubule assembly at the muscle-tendon junction. Subramanian, A., Prokop, A., Yamamoto, M., Sugimura, K., Uemura, T., Betschinger, J., Knoblich, J.A., Volk, T. Curr. Biol. (2003)
- Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling. Funayama, N., Fagotto, F., McCrea, P., Gumbiner, B.M. J. Cell Biol. (1995)
- Wingless eliminates ommatidia from the edge of the developing eye through activation of apoptosis. Lin, H.V., Rogulja, A., Cadigan, K.M. Development (2004)
- Activation of B cells using Schneider 2 cells expressing CD40 ligand for the enhancement of antigen presentation in vitro. Yoon, S.H., Cho, H.I., Kim, T.G. Exp. Mol. Med. (2005)