Your search matched a total of 104 documents. Results 1 - 10.
Homo sapiens
Gene: ... , in the fish species examined so far it is also peripherally expressed. All the subtypes except MC4R could... affinity and potency of MC4R- selective ligands. For these peptides, the affinity and activity at all three...Disease relevance of MC4R Mutations in MC4R are the most common genetic cause of obesity... / Synonyms: MC4-R
Mus musculus
Gene: ... Disease relevance of Mc4r These data demonstrate that melanocortin signalling transduced by Mc4r.... Oxygen consumption of Mc4r- null mice with similar body weights as WT controls was reduced by 20%. In response to moderately increased dietary fat content, melanocortin- 4 receptor- null mutant( MC4R -/-) mice... / Synonyms: MC4-R
Rattus norvegicus
Gene: ... Disease relevance of Mc4r For example, MC4- R deletion or mutation results in obesity, hyperphagia... melanocortin receptor- 4( MC4R) activation produces antipyretic effects, the MC4R selective agonist MRLOB- 0001... information on Mc4r Rats were fasted overnight to promote feeding behavior, then injected intraperitoneally... / Synonyms: MC4-R
Bos taurus
Gene: ... High impact information on MC4R We showed that Agrp inhibited, in a dose- dependent manner, the 10 (- 9) M NDP- alphaMSH- induced cortisol production through its antagonistic properties towards MSH at the level of MC4- R. Analytical, diagnostic and therapeutic context of MC4R The bovine MC4R gene was mapped...
Gallus gallus
Gene: ... High impact information on MC4R The alpha- MSH- elicited CORT release was not attenuated by the injection of agouti- related protein, an endogenous melanocortin- 4( MC4) receptor antagonist, suggesting... work on MC1R variants in horse, pig, and chicken, as well as a study on MC4R polymorphism in the pig...
Sus scrofa
Gene: ... Disease relevance of MC4R The melanocortin 4 receptor( MC4R) is a key factor in the regulation of energy balance and body weight. The melanocortin- 4 receptor( MC4R) has a vital role in the control of energy balance and the genetic basis of obesity. High impact information on MC4R This methodology...
MeSH term: ... demonstrate that melanocortin signalling transduced by Mc4r is not an exclusive target of leptin action... to MC4R haploinsufficiency. These findings support an important role for PLIN as a candidate gene...
MeSH term: ... Disease relevance of Mice, Transgenic Overexpression of TGF alpha in the mammary epithelium, as confirmed by in situ hybridization and immunohistochemistry, is associated with hyperplasia of alveoli and terminal ducts in virgin female and pregnant transgenic mice. Restoration of MC4R expression...
MeSH term: ... is chronic antagonism of the MC4- R. To evaluate the effect of endotoxin on the fibrinolytic response, we... days. All patients received 15 mg of albendazole per kilogram of body weight per day for four weeks...
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Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
