Disease relevance of Entamide

• The present studies show that diloxanide furoate is an effective treatment of amebiasis in asymptomatic patients [1].
• Efficacy of a combined diloxanide furoate-metronidazole preparation in the treatment of amoebiasis and giardiasis [2].

High impact information on Entamide

• Quinolinol, mebendazole, diloxanide furoate, and albendazole had no demonstrable efficacy in vitro [3].
• All cyclodextrins studied provided a stabilizing effect to diloxanide furoate hydrolysis [4].
• Comparative in vitro activity of mefloquine, diloxanide furoate and other conventionally used amoebicides against entamoeba histolytica [5].

Chemical compound and disease context of Entamide

• Treatment of asymptomatic amebiasis in homosexual men. Clinical trials with metronidazole, tinidazole, and diloxanide furoate [1].
• Treatment of amoebiasis with metronidazole and entamide furoate [6].
• Additive effect of diloxanide furoate and metronidazole (Entamizole) in experimental mouse caecal amoebiasis [7].

Associations of Entamide with other chemical compounds

• Three hydrolysis products of a basic methanolic solution of the drug, namely furoic acid, diloxanide and methylfuroate could be identified by the use of TLC, HPLC, infrared and mass spectrometry [8].

Analytical, diagnostic and therapeutic context of Entamide

• Among the men treated with diloxanide furoate, the PCR was 93% [1].
• The degradation of the amoebicide diloxanide furoate in alkaline medium at different temperatures was investigated using both a spectrophotometric and a developed HPLC method [8].

References