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Chemical Compound Review

CHEMBL87658     N-(2-chloroethyl)-2-oxo-1- oxa-3-aza...

Synonyms: ASTA 4968, AC1Q6TBW, LS-99793, AR-1J7771, AKOS006276510, ...
 
 
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Disease relevance of N-Dechloroethylcyclophosphamide

 

High impact information on N-Dechloroethylcyclophosphamide

 

Analytical, diagnostic and therapeutic context of N-Dechloroethylcyclophosphamide

References

  1. Population Pharmacokinetics of the BEACOPP Polychemotherapy Regimen in Hodgkin's Lymphoma and its Effect on Myelotoxicity. Wilde, S., Jetter, A., Rietbrock, S., Kasel, D., Engert, A., Josting, A., Klimm, B., Hempel, G., Reif, S., Jaehde, U., Merkel, U., Busse, D., Schwab, M., Diehl, V., Fuhr, U. Clinical pharmacokinetics (2007) [Pubmed]
  2. Dose escalation of cyclophosphamide in patients with breast cancer: consequences for pharmacokinetics and metabolism. Busse, D., Busch, F.W., Bohnenstengel, F., Eichelbaum, M., Fischer, P., Opalinska, J., Schumacher, K., Schweizer, E., Kroemer, H.K. J. Clin. Oncol. (1997) [Pubmed]
  3. Cytogenetic mechanisms in the selective toxicity of cyclophosphamide analogs and metabolites towards avian embryonic B lymphocytes in vivo. Wilmer, J.L., Colvin, O.M., Bloom, S.E. Mutat. Res. (1992) [Pubmed]
  4. Pharmacokinetics and metabolism of cyclophosphamide in paediatric patients. Tasso, M.J., Boddy, A.V., Price, L., Wyllie, R.A., Pearson, A.D., Idle, J.R. Cancer Chemother. Pharmacol. (1992) [Pubmed]
  5. Characterization of the cytochrome P450 involved in side-chain oxidation of cyclophosphamide in humans. Bohnenstengel, F., Hofmann, U., Eichelbaum, M., Kroemer, H.K. Eur. J. Clin. Pharmacol. (1996) [Pubmed]
 
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