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Chemical Compound Review

KST-1A9171     (3R)-2,3-dihydroxybutanedioic acid; 2...

Synonyms: AR-1A2644, LS-123098, AC1L3RL1, AC1Q5R3K, UNII-B6DRB5ZI7P, ...
 
 
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Disease relevance of Su 4885

 

High impact information on Su 4885

 

Analytical, diagnostic and therapeutic context of Su 4885

  • Metyrapone tartrate testing was used to assess the function of the hypothalamic-pituitary-adrenal (HPA) axis during, after, and, in one case, before the drug therapy [6].

References

  1. The effects of agents that bind to cytochrome P-450 on hypoxic pulmonary vasoconstriction. Sylvester, J.T., McGowan, C. Circ. Res. (1978) [Pubmed]
  2. Steroidogenesis of the fetal adrenal gland in vitro: influence of metopirone applied in vivo and in vitro. Klepac, R., Milković, K., Paunović, J., Milković, S. Proc. Soc. Exp. Biol. Med. (1975) [Pubmed]
  3. Effect of the adrenocorticostatic agent, metopirone, on thermoregulatory heat production in the European hedgehog*. Werner, R., Wünnenberg, W. Pflugers Arch. (1980) [Pubmed]
  4. Effectiveness of methyrapone in the treatment of acetaminophen toxicity in mice. Nelson, E.B., Montes, M., Goldstein, M. Toxicology (1980) [Pubmed]
  5. Intravenous metyrapone testing. Evaluation of growth hormone and adrenocorticotrophic hormone in children. Bacon, G.E., Larson, R.M., Spencer, M.L., Kelch, R.P. Am. J. Dis. Child. (1975) [Pubmed]
  6. Long-term intramuscular administration of triamcinolone acetonide. Effect on the hypothalamic-pituitary-adrenal axis. Carson, T.E., Daane, T.A., Weinstein, R.L. Archives of dermatology. (1975) [Pubmed]
 
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