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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Bayrepel     butan-2-yl2-(2- hydroxyethyl)piperidine-1...

Synonyms: Icaridin, Icaridina, Icaridine, Picaridin, Pikaridin, ...
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Disease relevance of Bayrepel

  • The response of field populations of Cx. annulirostris, an important vector of arboviruses in Australia, to repellents containing deet and picaridin is reported for the first time [1].

High impact information on Bayrepel

  • Synthetic insect repellents, IR3535 and KBR 3023 (also known as picaridin, or by the trade name Bayrepel, were tested in Burkina Faso against mosquito vectors of disease to compare their relative efficacy and persistence profiles to those of the 'gold standard' DEET [2].
  • Compounds of more recent research are MERCK 3535 (aminopropionic acid ethylester), p-menthane-3,8 diol, CIC 4 (a lacton) and the piperidine derivatives AI3-37220 and Bayrepel (Icaridin) [3].
  • Moreover, protection afforded by Deet, SS220, and Picaridin against the feeding of these three disease vectors on humans is mechanistically a consequence of the two chemical effects [4].
  • Synthesis and repellent efficacy of a new chiral piperidine analog: comparison with Deet and Bayrepel activity in human-volunteer laboratory assays against Aedes aegypti and Anopheles stephensi [5].
  • Four insect repellent products (RPs) (RP 1, Experimental Repellent Lotion [Bayrepel 12%]; RP 2, Experimental Repellent Cream [Bayrepel 5%]; RP 3, Off! Insect Repellent II Aerosol [deet 15%]; and RP 4, Off! Skintastic II Cream [deet 7.5%]) were evaluated simultaneously for their efficacy against vector and nuisance mosquitoes [6].

Analytical, diagnostic and therapeutic context of Bayrepel

  • Quantitative laboratory assays using human volunteers compared the effectiveness of SS220 with the commonly used repellents Deet and Bayrepel against Aedes aegypti (Linnaeus) and Anopheles stephensi Liston mosquitoes [5].


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