Disease relevance of Burkina Faso

• Epilepsy in a focus of onchocerciasis in Burkina Faso [1].
• In contrast, in Benin and Burkina Faso, both mesoendemic regions for Plasmodium falciparum malaria and other infections due to intestinal parasites, a low incidence of Chit mutation was found (heterozygous 0 and 2%, respectively) and no subject was homozygous for Chit deficiency [2].
• TNF as a malaria candidate gene: polymorphism-screening and family-based association analysis of mild malaria attack and parasitemia in Burkina Faso [3].
• In Niamey, only sporadic cases were reported: 55% of the meningococcus strains were in serogroup A, and 38% were in serogroup W135 and could be placed in ST-11, identical to the 2002 Burkina Faso epidemic clone, and in ST-2881, a new ST [4].
• To determine the effect of chloroquine chemoprophylaxis during pregnancy on birth weights, a randomized trial was carried out in 1987 and 1988 in Banfora, Burkina Faso (West Africa) [5].

Psychiatry related information on Burkina Faso

• Milk from 101 mothers living in Ouagadougou (Burkina Faso) showed a mean lipid content of 33.42 g/l and a fatty acid composition strongly related to the mothers' dietary habits: high proportions of linoleic acid (19.80%), n-6 long-chain polyunsaturated fatty acids (1.90%), and 8:0-14:0 saturated fatty acids (26.94%) [6].

High impact information on Burkina Faso

• METHODS: A randomised double-blind placebo-controlled trial was carried out in public clinics of Abidjan, Côte d'Ivoire, and Bobo-Dioulasso, Burkina Faso [7].
• BACKGROUND: On March 21, 1998, the Regional Health Authority of Bobo-Dioulasso, Burkina Faso, asked the Centre Muraz to investigate an unexplained outbreak of epidemic fatal encephalopathy (EFE) [8].
• A case of epidermodysplasia verruciformis in a patient from Upper-Volta is described [9].
• Sera collected during the post-epidemic period (1970 to 1977) in Senegal, Sierra Leone, Mali, Upper Volta, Chad, Niger and Gabon were also examined; 1573 (68%) were VN antibody negative (less than or equal to 1:4), while 733 (32%) and 433 (19%) had titers of 1:8 or greater and 1:16 or over, respectively [10].
• In two phase II clinical trials on methylene blue (MB) antimalarial therapy in rural Burkina Faso, paediatric and adult participants were tested for G6PD deficiency [11].

Chemical compound and disease context of Burkina Faso

• Increasing resistance to chloroquine necessitates the evaluation of other antimalarial therapies in Africa. We compared the efficacies of amodiaquine (AQ), sulfadoxine-pyrimethamine (SP), and AQ + SP for the treatment of uncomplicated falciparum malaria in a randomized trial of patients 6 months of age or older in Bobo-Dioulasso, Burkina Faso [12].
• This report strongly supports the existence of mefloquine-resistant falciparum malaria in West Africa, especially in Sierra Leone, Burkina Faso, and Cote d'Ivoire [13].
• BACKGROUND: Low levels of plasma homocysteine have been found in children and adult populations living in Burkina Faso in association with a low prevalence of coronary heart disease [14].
• This paper proposes a new approach to the economics of blindness prevention under the Onchocerciasis Control Program in Upper Volta [15].
• The model is illustrated using onchocerciasis prevalence data collected from nine West African village communities in 1975 and 1981, before and after the implementation of widespread larvacide controls as part of the O.C.P. in the Upper Volta region [16].

Biological context of Burkina Faso

• Four Trypanosoma (T.) congolense reference clones with known isometamidium sensitivity and 16 T. congolense stocks from cattle in Kénédougou in south-western Burkina Faso, an area with known history of drug resistance, were characterised with the standard mouse test (SMT) and the drug incubation infectivity test (DIIT) [17].
• Preliminary data indicate no differences in the fecundity of X(A)X(A) and X(A)X(B) females, but there are indications that G. m. submorsitans in colonies originating from Burkina Faso and Nigeria have genes on the autosomes and (or) the Y chromosome that suppress expression of sex-ratio distortion [18].
• BACKGROUND: Vitamin A deficiency remains a public health problem in Burkina Faso and elsewhere in the developing world [19].
• In the Upper Region along the border with Upper Volta now named Burkina Faso, a total of 185 clay-core dams were constructed in 15 years to enhance village water supplies during the 6-month dry season [20].
• Sera from individuals in the process of either acquiring natural resistance (from different age groups in a village of Upper Volta) or losing acquired resistance (adults travelling from hyperendemic areas of Africa to France) were compared [21].

Associations of Burkina Faso with chemical compounds

• Plasmodium falciparum susceptibility to halofantrine hydrochloride was investigated in a small village near Ouagadougou, Burkina Faso, where the parasite was known to be chloroquine resistant [22].
• Influence of deltamethrin treatment of bed nets on malaria transmission in the Kou valley, Burkina Faso [23].
• We report the results of a cross-sectional study carried out in 1995-96 on anaemia in pregnant women who were attending two antenatal clinics in Bobo-Dioulasso, Burkina Faso, as part of a research programme including a clinical trial of zidovudine (ZDV) in pregnancy (ANRS 049 Clinical Trial) [24].
• Elevated levels of plasma homocysteine in postmenopausal women in Burkina Faso [14].
• This clone was derived, without drug selection, from a stock originally isolated in Burkina Faso and has previously been shown to be resistant to isometamidium in both cattle and mice using an infection and treatment regimen [25].

Gene context of Burkina Faso

• Diagnosis of red cell G6PD deficiency in rural Burkina Faso: comparison of a rapid fluorescent enzyme test on filter paper with polymerase chain reaction based genotyping [11].
• IPOX was calibrated after real scale tests performed in Spain and Burkina Faso [26].
• The ST-11 complex was characterized by serogroup W135, which has been responsible for an increasing number of sporadic cases since 2000 and the first W135 epidemic ever seen in Africa (in Burkina Faso in 2002) [27].
• beta 2-Microglobulin (beta 2m) levels were related to the expected immunoprotection in 81 individuals living in a malarial mesoendemic area near Bobo-Dioulasso (Burkina Faso), who were longitudinally followed [28].
• Serological evaluation of a simplified immunization schedule using quadruple DPT-polio vaccine in Burkina Faso [29].

Analytical, diagnostic and therapeutic context of Burkina Faso

• PCR was used to detect trypanosome infections prior to, 14 and 28 days after controlled treatment of 738 cattle from 10 villages in Kénédougou, Burkina Faso with isometamidium chloride and diminazene aceturate [30].
• The performance of indirect haemagglutination assays (IHA), enzyme-linked immunosorbent assays (ELISA) and indirect immunofluorescent antibody tests (IFAT) were compared with 450 sera from a Schistosoma mansoni-endemic area in Burkina Faso [31].
• The oestrous response, interval and conception rates were studied after synchronization with a prostaglandin analogue (cloprostenol) and artificial insemination (AI) performed at different times in 50 Zebu (Bos indicus) and 83 Baoulé (Bos taurus) cattle indigenous to Burkina Faso [32].

References