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Chemical Compound Review:

Acetylfuran 1-(2-furyl)ethanone

Synonyms: PubChem6939, SureCN43960, AGN-PC-006I35, NSC-4665, ACMC-1BPS0, ...

Totlani, V.M. et al., Kawai, T. et al., Corsi, G.C. et al.

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Disease relevance of Acetylfuran

Calculation of the GOT/GPT ratios indicated a pattern of toxic hepatitis only for rats treated with acetylfuran and furan + methylene chloride [1].

High impact information on Acetylfuran

Quantitative gas chromatography (GC) analysis indicated that the addition of epicatechin to glucose or fructose/glycine model systems significantly reduced the generation of hydroxyacetone, 2-methylpyrazine, 2,3,5-trimethylpyrazine, furfural, 2-acetylfuran, 5-methylfurfural, 2(5H)-furanone, 2-acetylpyrrole, and furfuryl alcohol [2].
The formation of a compound, identified by gas chromatography-mass spectrometry (GC-MS) as 2-acetylfuran, following acid hydrolysis was a major cause of confounding effects [3].

References

Effect of subtoxic amounts of furan, acetylfuran and methylene chloride on some serum enzymes of rat. Corsi, G.C., Valentini, F., Bertazzon, A. Boll. Soc. Ital. Biol. Sper. (1983) [Pubmed]
Influence of epicatechin reactions on the mechanisms of Maillard product formation in low moisture model systems. Totlani, V.M., Peterson, D.G. J. Agric. Food Chem. (2007) [Pubmed]
2-Acetylfuran, a confounder in urinalysis for 2,5-hexanedione as an n-hexane exposure indicator. Kawai, T., Yasugi, T., Mizunuma, K., Horiguchi, S., Uchida, Y., Iwami, O., Iguchi, H., Ikeda, M. International archives of occupational and environmental health. (1991) [Pubmed]

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