High impact information on Sodium dioctyl sulfosuccinate

• All the 16 PAHs were baseline-resolved using an optimized running buffer containing 22.5 mM DOSS, 15 mM SB-beta-CD, 15% acetonitrile and 5 mM hydroxypropyl-beta-cyclodextrin in 6 mM borate at pH 9 [1].
• Sodium dioctyl sulfosuccinate (DOSS) displayed selectivities for PAHs which were somewhat similar to the C18 phase in reversed-phase high performance liquid chromatography (HPLC) [1].
• The process is accompanied by an increase in the steady-state anisotropy, as opposed to what happens for denaturation in aqueous solution.Since 1-hexanol used as co-surfactant in dioctyl sulfosuccinate reverse micelles slows or even prevents cutinase denaturation, its effect on cutinase conformation and on the size of reverse micelles was analyzed [2].
• This is attributed to a favourable stereoelectronic interaction between DSS and the nucleus of melatonin, which seems to be independent of the pH of the dissolution medium [3].
• At pH 4.0, the transport of methotrexate was enhanced by the counter ions and a marked increase in the flux of the drug was measured when dodecyl sulfate and dioctyl sulfosuccinate were used [4].

Associations of Sodium dioctyl sulfosuccinate with other chemical compounds

• To analyze lipophilic antioxidants, an optically clear organic system composed of diethyl ether, surfactant (dioctyl sulfosuccinate, AOT) and water, called reverse micelles, was developed [5].

References