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Chemical Compound Review

Ketogin     N,N-dimethyl-4,4-diphenyl- but-3-en-2...

Synonyms: AC1L4N0N
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Disease relevance of Ketogan


High impact information on Ketogan


Associations of Ketogan with other chemical compounds


Analytical, diagnostic and therapeutic context of Ketogan

  • Thirteen cancer patients with moderate to severe chronic pain of malignant origin on treatment with Ketogan tablets were included in an open non-randomized cross-over study comparing the analgesic effect, side effects and serum concentrations of Ketogan tablets and mixture [4].
  • For pain-score the difference was significant (p = 0.02) in arthrodesis/arthroplasty patients day 1 and for need for Ketogan injections (p less than 0.001) in all patients day 0 [7].


  1. Analgesic treatment in acute myocardial infarction. A double-blind comparison of ketobemidone + the spasmolytic A29 (Ketogan) and morphine. Wolff, T., Leward, S., Hagman, A., Andersson, M., Larsson, L., Elgen, K. Acta medica Scandinavica. (1988) [Pubmed]
  2. Analgetic effects of indomethacin (Confortid) compared to Ketogin in patients with acute cholecystitis. Mätzsch, T., Holmlund, D. Scandinavian journal of urology and nephrology. Supplementum. (1983) [Pubmed]
  3. Premedication before elective breast surgery, a comparison between ketobemidone and midazolam. Jakobsson, J., Andersson, L., Nilsson, A., Davidson, S., Askergren, J. Acta anaesthesiologica Scandinavica. (1991) [Pubmed]
  4. Analgesic effect and bioavailability of oral ketogan given as tablets or mixture to patients with chronic pain of malignant origin. Kjaer, M., Nielsen, H. Acta oncologica (Stockholm, Sweden) (1988) [Pubmed]
  5. Validation of urine drug-of-abuse testing methods for ketobemidone using thin-layer chromatography and liquid chromatography-electrospray mass spectrometry. Breindahl, T., Andreasen, K. J. Chromatogr. B Biomed. Sci. Appl. (1999) [Pubmed]
  6. Single-dose kinetics and bioavailability of ketobemidone. Anderson, P., Arnér, S., Bondesson, U., Boréus, L.O., Hartvig, P. Acta anaesthesiologica Scandinavica. Supplementum. (1982) [Pubmed]
  7. Naproxen suppositories in postoperative pain and swelling after joint surgery. A comparative, double-blind study. Kvarnes, L. Scand. J. Rheumatol. (1984) [Pubmed]
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