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Disease relevance of Arthroplasty


Psychiatry related information on Arthroplasty

  • Analyses examined the relationship of 5 Centers for Disease Control and Prevention HRQOL items (general health, mental health, pain, activity limitation, and sleep) to physician visits, prescription analgesic or antiinflammatory use, and arthroplasty during 1 year of followup [6].
  • The prognosis of rheumatoid arthritis is best described separately for mortality, work disability, costs, functional disability, total joint arthroplasty, radiographic abnormality, and psychosocial factors [7].

High impact information on Arthroplasty


Chemical compound and disease context of Arthroplasty


Biological context of Arthroplasty

  • These results suggest that treatment in the perioperative period with weekly low-dose pulse MTX does not increase the risk of local postoperative infectious complications or poor wound healing in rheumatoid arthritis patients who undergo total joint arthroplasty [18].
  • We studied the effect of a single-dose infusion of 90 mg of pamidronate on early periprosthetic bone mineral density (BMD), biochemical markers of bone turnover, radiological, and clinical outcome in a 26-week, prospective, randomized, double-blinded study of 47 men and women undergoing total hip arthroplasty [19].
  • Twenty-eight patients undergoing total hip or knee arthroplasty completed a randomized, placebo-controlled, double-blinded trial of 50 mg of amitriptyline p.o. HS on postoperative days 1, 2 and 3 while using patient-controlled morphine or meperidine analgesia (PCA) [20].
  • The presence of icaA in a coagulase-negative staphylococcal isolate associated with an arthroplasty is not a useful diagnostic indicator of pathogenicity [21].
  • Large-dose administration of 6% hydroxyethyl starch 200/0.5 total hip arthroplasty: plasma homeostasis, hemostasis, and renal function compared to use of 5% human albumin [22].

Anatomical context of Arthroplasty


Associations of Arthroplasty with chemical compounds

  • We performed a 10-year retrospective analysis of the frequency of local postoperative infectious complications in methotrexate (MTX)-treated rheumatoid arthritis patients who underwent total joint arthroplasty [18].
  • Low-molecular-weight heparin prophylaxis using dalteparin in close proximity to surgery vs warfarin in hip arthroplasty patients: a double-blind, randomized comparison. The North American Fragmin Trial Investigators [28].
  • Alendronate reduces periprosthetic bone loss after uncemented primary total hip arthroplasty: a prospective randomized study [29].
  • Effect of pamidronate in preventing local bone loss after total hip arthroplasty: a randomized, double-blind, controlled trial [19].
  • The fractal dimension of trabecular bone was determined for biopsies from the proximal femur of 25 subjects undergoing hip arthroplasty [30].

Gene context of Arthroplasty


Analytical, diagnostic and therapeutic context of Arthroplasty


  1. Extended out-of-hospital low-molecular-weight heparin prophylaxis against deep venous thrombosis in patients after elective hip arthroplasty: a systematic review. Hull, R.D., Pineo, G.F., Stein, P.D., Mah, A.F., MacIsaac, S.M., Dahl, O.E., Butcher, M., Brant, R.F., Ghali, W.A., Bergqvist, D., Raskob, G.E. Ann. Intern. Med. (2001) [Pubmed]
  2. Prevention of venous thromboembolism after knee arthroplasty. A randomized, double-blind trial comparing enoxaparin with warfarin. Leclerc, J.R., Geerts, W.H., Desjardins, L., Laflamme, G.H., L'Espérance, B., Demers, C., Kassis, J., Cruickshank, M., Whitman, L., Delorme, F. Ann. Intern. Med. (1996) [Pubmed]
  3. Direct evidence of high DNA binding activity of transcription factor AP-1 in rheumatoid arthritis synovium. Asahara, H., Fujisawa, K., Kobata, T., Hasunuma, T., Maeda, T., Asanuma, M., Ogawa, N., Inoue, H., Sumida, T., Nishioka, K. Arthritis Rheum. (1997) [Pubmed]
  4. Decreases in rates of hospitalizations for manifestations of severe rheumatoid arthritis, 1983-2001. Ward, M.M. Arthritis Rheum. (2004) [Pubmed]
  5. Variation in the TNF gene promoter and risk of osteolysis after total hip arthroplasty. Wilkinson, J.M., Wilson, A.G., Stockley, I., Scott, I.R., Macdonald, D.A., Hamer, A.J., Duff, G.W., Eastell, R. J. Bone Miner. Res. (2003) [Pubmed]
  6. Health-related quality of life and health service use among older adults with osteoarthritis. Dominick, K.L., Ahern, F.M., Gold, C.H., Heller, D.A. Arthritis Rheum. (2004) [Pubmed]
  7. The prognosis of rheumatoid arthritis: assessment of disease activity and disease severity in the clinic. Wolfe, F. Am. J. Med. (1997) [Pubmed]
  8. Low molecular weight heparin: a critical analysis of clinical trials. Green, D., Hirsh, J., Heit, J., Prins, M., Davidson, B., Lensing, A.W. Pharmacol. Rev. (1994) [Pubmed]
  9. Capturing the patient's view of change as a clinical outcome measure. Fischer, D., Stewart, A.L., Bloch, D.A., Lorig, K., Laurent, D., Holman, H. JAMA (1999) [Pubmed]
  10. Aspirin-sulfinpyrazone in prophylaxis of deep venous thrombosis in total hip replacement. Sautter, R.D., Koch, E.L., Myers, W.O., Ray, J.R., Mazza, J.J., Larson, D.E., Chen, H.M., Milbauer, J.P., Treuhaft, P.S., Plotka, E.D. JAMA (1983) [Pubmed]
  11. Prevalence of arthroplasty during the course of rheumatoid arthritis. Block, J.A. Lancet (1998) [Pubmed]
  12. Effect of non-steroidal anti-inflammatory drugs on the course of osteoarthritis. Rashad, S., Revell, P., Hemingway, A., Low, F., Rainsford, K., Walker, F. Lancet (1989) [Pubmed]
  13. Mycoplasma felis septic arthritis in a patient with hypogammaglobulinemia. Bonilla, H.F., Chenoweth, C.E., Tully, J.G., Blythe, L.K., Robertson, J.A., Ognenovski, V.M., Kauffman, C.A. Clin. Infect. Dis. (1997) [Pubmed]
  14. Aseptic loosening in total hip arthroplasty secondary to osteolysis induced by wear debris from titanium-alloy modular femoral heads. Harris, W.H. The Journal of bone and joint surgery. American volume. (1991) [Pubmed]
  15. Alumina-on-alumina total hip arthroplasty. A five-year minimum follow-up study. Yoo, J.J., Kim, Y.M., Yoon, K.S., Koo, K.H., Song, W.S., Kim, H.J. The Journal of bone and joint surgery. American volume. (2005) [Pubmed]
  16. Prevention of deep-vein thrombosis after total knee arthroplasty in Asian patients. Comparison of low-molecular-weight heparin and indomethacin. Wang, C.J., Wang, J.W., Weng, L.H., Hsu, C.C., Huang, C.C., Yu, P.C. The Journal of bone and joint surgery. American volume. (2004) [Pubmed]
  17. Tranexamic acid reduces postoperative blood loss in cementless total hip arthroplasty. Yamasaki, S., Masuhara, K., Fuji, T. The Journal of bone and joint surgery. American volume. (2005) [Pubmed]
  18. Local infectious complications following large joint replacement in rheumatoid arthritis patients treated with methotrexate versus those not treated with methotrexate. Perhala, R.S., Wilke, W.S., Clough, J.D., Segal, A.M. Arthritis Rheum. (1991) [Pubmed]
  19. Effect of pamidronate in preventing local bone loss after total hip arthroplasty: a randomized, double-blind, controlled trial. Wilkinson, J.M., Stockley, I., Peel, N.F., Hamer, A.J., Elson, R.A., Barrington, N.A., Eastell, R. J. Bone Miner. Res. (2001) [Pubmed]
  20. Low-dose amitriptyline as an adjunct to opioids for postoperative orthopedic pain: a placebo-controlled trial. Kerrick, J.M., Fine, P.G., Lipman, A.G., Love, G. Pain (1993) [Pubmed]
  21. icaA is not a useful diagnostic marker for prosthetic joint infection. Frank, K.L., Hanssen, A.D., Patel, R. J. Clin. Microbiol. (2004) [Pubmed]
  22. Large-dose administration of 6% hydroxyethyl starch 200/0.5 total hip arthroplasty: plasma homeostasis, hemostasis, and renal function compared to use of 5% human albumin. Vogt, N.H., Bothner, U., Lerch, G., Lindner, K.H., Georgieff, M. Anesth. Analg. (1996) [Pubmed]
  23. Erythropoietin for total hip joint arthroplasty. Kontor, J.T. Ann. Intern. Med. (2001) [Pubmed]
  24. Correlation of power Doppler sonography with vascularity of the synovial tissue of the knee joint in patients with osteoarthritis and rheumatoid arthritis. Walther, M., Harms, H., Krenn, V., Radke, S., Faehndrich, T.P., Gohlke, F. Arthritis Rheum. (2001) [Pubmed]
  25. Transforming growth factor-beta2 suppresses collagen cleavage in cultured human osteoarthritic cartilage, reduces expression of genes associated with chondrocyte hypertrophy and degradation, and increases prostaglandin E(2) production. Tchetina, E.V., Antoniou, J., Tanzer, M., Zukor, D.J., Poole, A.R. Am. J. Pathol. (2006) [Pubmed]
  26. Large and small proteoglycans of osteoarthritic and rheumatoid articular cartilage. Cs-Szabó, G., Roughley, P.J., Plaas, A.H., Glant, T.T. Arthritis Rheum. (1995) [Pubmed]
  27. Effect of osteoprotegerin and osteoprotegerin ligand on osteoclast formation by arthroplasty membrane derived macrophages. Itonaga, I., Sabokbar, A., Murray, D.W., Athanasou, N.A. Ann. Rheum. Dis. (2000) [Pubmed]
  28. Low-molecular-weight heparin prophylaxis using dalteparin in close proximity to surgery vs warfarin in hip arthroplasty patients: a double-blind, randomized comparison. The North American Fragmin Trial Investigators. Hull, R.D., Pineo, G.F., Francis, C., Bergqvist, D., Fellenius, C., Soderberg, K., Holmqvist, A., Mant, M., Dear, R., Baylis, B., Mah, A., Brant, R. Arch. Intern. Med. (2000) [Pubmed]
  29. Alendronate reduces periprosthetic bone loss after uncemented primary total hip arthroplasty: a prospective randomized study. Venesmaa, P.K., Kröger, H.P., Miettinen, H.J., Jurvelin, J.S., Suomalainen, O.T., Alhav, E.M. J. Bone Miner. Res. (2001) [Pubmed]
  30. Fractal dimension and architecture of trabecular bone. Fazzalari, N.L., Parkinson, I.H. J. Pathol. (1996) [Pubmed]
  31. Tumor necrosis factor-alpha mediates orthopedic implant osteolysis. Merkel, K.D., Erdmann, J.M., McHugh, K.P., Abu-Amer, Y., Ross, F.P., Teitelbaum, S.L. Am. J. Pathol. (1999) [Pubmed]
  32. Periprosthetic osteolysis: induction of vascular endothelial growth factor from human monocyte/macrophages by orthopaedic biomaterial particles. Miyanishi, K., Trindade, M.C., Ma, T., Goodman, S.B., Schurman, D.J., Smith, R.L. J. Bone Miner. Res. (2003) [Pubmed]
  33. Increased CD40 expression on articular chondrocytes from patients with rheumatoid arthritis: contribution to production of cytokines and matrix metalloproteinases. Gotoh, H., Kawaguchi, Y., Harigai, M., Hara, M., Saito, S., Yamaguchi, T., Shimada, K., Kawamoto, M., Tomatsu, T., Kamatani, N. J. Rheumatol. (2004) [Pubmed]
  34. Release of interleukin-10 by reinfusion of salvaged blood after knee arthroplasty. Tylman, M., Bengtson, J.P., Avall, A., Hyllner, M., Bengtsson, A. Intensive care medicine. (2001) [Pubmed]
  35. Erythropoietin with iron supplementation to prevent allogeneic blood transfusion in total hip joint arthroplasty. A randomized, controlled trial. Feagan, B.G., Wong, C.J., Kirkley, A., Johnston, D.W., Smith, F.C., Whitsitt, P., Wheeler, S.L., Lau, C.Y. Ann. Intern. Med. (2000) [Pubmed]
  36. Efficacy and cost of low-molecular-weight heparin compared with standard heparin for the prevention of deep vein thrombosis after total hip arthroplasty. Anderson, D.R., O'Brien, B.J., Levine, M.N., Roberts, R., Wells, P.S., Hirsh, J. Ann. Intern. Med. (1993) [Pubmed]
  37. Comparison of native prothrombin antigen with the prothrombin time for monitoring oral anticoagulant prophylaxis. Kornberg, A., Francis, C.W., Pellegrini, V.D., Gabriel, K.R., Marder, V.J. Circulation (1993) [Pubmed]
  38. Pharmacokinetic study of ceftazidime in bone and serum of patients undergoing hip and knee arthroplasty. Leigh, D.A., Griggs, J., Tighe, C.M., Powell, H.D., Church, J.C., Wise, K., Channon, G., Curtis, L.B. J. Antimicrob. Chemother. (1985) [Pubmed]
  39. Results after hemiarthroplasty of the hip using a cemented femoral prosthesis. A review of 109 cases with an average follow-up of 36 months. Beckenbaugh, R.D., Tressler, H.A., Johnson, E.W. Mayo Clin. Proc. (1977) [Pubmed]
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