Chemical Compound Review:
SAICAR (2S)-2-[[5-amino-1- [(2R,3R,4S,5R)-3,4...
Synonyms:
SAICAriboside, Succino-AICAR, SureCN73325, AG-E-99788, HMDB00797, ...
- Cloning of a chicken liver cDNA encoding 5-aminoimidazole ribonucleotide carboxylase and 5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase by functional complementation of Escherichia coli pur mutants. Chen, Z.D., Dixon, J.E., Zalkin, H. Proc. Natl. Acad. Sci. U.S.A. (1990)
- Structure of SAICAR synthase from Thermotoga maritima at 2.2 angstroms reveals an unusual covalent dimer. Zhang, R., Skarina, T., Evdokimova, E., Edwards, A., Savchenko, A., Laskowski, R., Cuff, M.E., Joachimiak, A. Acta Crystallograph. Sect. F Struct. Biol. Cryst. Commun. (2006)
- Yeast AMP pathway genes respond to adenine through regulated synthesis of a metabolic intermediate. Rébora, K., Desmoucelles, C., Borne, F., Pinson, B., Daignan-Fornier, B. Mol. Cell. Biol. (2001)
- Clinical, biochemical and molecular genetic correlations in adenylosuccinate lyase deficiency. Race, V., Marie, S., Vincent, M.F., Van den Berghe, G. Hum. Mol. Genet. (2000)
- Expression, purification, and kinetic characterization of recombinant human adenylosuccinate lyase. Stone, R.L., Zalkin, H., Dixon, J.E. J. Biol. Chem. (1993)
- Purification and characterization of the purE, purK, and purC gene products: identification of a previously unrecognized energy requirement in the purine biosynthetic pathway. Meyer, E., Leonard, N.J., Bhat, B., Stubbe, J., Smith, J.M. Biochemistry (1992)
- Preparation of 5-amino-4-imidazole-N-succinocarboxamide ribotide, 5-amino-4-imidazole-N-succinocarboxamide riboside and succinyladenosine, compounds usable in diagnosis and research of adenylosuccinate lyase deficiency. Zikánová, M., Krijt, J., Hartmannová, H., Kmoch, S. J. Inherit. Metab. Dis. (2005)
- DNA-bound Bas1 recruits Pho2 to activate ADE genes in Saccharomyces cerevisiae. Som, I., Mitsch, R.N., Urbanowski, J.L., Rolfes, R.J. Eukaryotic Cell (2005)
- Two complementary radiometric methods for the measurement of 5-amino-4-imidazole-N-succinocarboxamide ribonucleotide synthetase (SAICAR synthetase). Tyagi, A.K., Cooney, D.A., Bledsoe, M., Jayaram, H.N. J. Biochem. Biophys. Methods (1980)