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Chemical Compound Review

PubChem10770     1,2-dichloro-3-nitro-benzene

Synonyms: SureCN58157, AGN-PC-00GTW6, CHEMBL168024, ACMC-1CCAW, CCRIS 5901, ...
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Disease relevance of NSC60641

  • Recently we encountered a patient (p1) with a Clark's level IV melanoma associated with recurrent cutaneous metastasis who subsequently experienced a complete remission after a period of therapy with dichloronitrobenzene (DCNB) and interferon-alpha (IFNalpha) [1].

High impact information on NSC60641


  1. Favourable melanoma prognosis associated with the expression of the tumour necrosis factor receptor and the alpha1beta1 integrin: a preliminary report. Gilhar, A., Ullmann, Y., Kalish, R.S., Berkutski, T., Azizi, E., Bank, I. Melanoma Res. (1997) [Pubmed]
  2. Biochemical basis for the extreme sensitivity of turkeys to aflatoxin B(1). Klein, P.J., Buckner, R., Kelly, J., Coulombe, R.A. Toxicol. Appl. Pharmacol. (2000) [Pubmed]
  3. Comparisons of phase I and phase II in vitro hepatic enzyme activities of human, dog, rhesus monkey, and cynomolgus monkey. Sharer, J.E., Shipley, L.A., Vandenbranden, M.R., Binkley, S.N., Wrighton, S.A. Drug Metab. Dispos. (1995) [Pubmed]
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