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Chemical Compound Review

Arofuto     6-amino-2-(fluoromethyl)-3- (2...

Synonyms: Afloqualon, Afloqualona, Aroft, afloqualone, Afloqualonum, ...
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Analytical, diagnostic and therapeutic context of Arofuto

  • The disposition and metabolism of afloqualone [6-amino-2-fluoromethyl-3-(o-tolyl)-4(3H)-quinazolinone, AFQ] were studied in monkeys and dogs after oral administration of 14C-AFQ [6].


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  4. Characterization of afloqualone N-glucuronidation: species differences and identification of human UDP-glucuronosyltransferase isoform(s). Kaji, H., Kume, T. Drug Metab. Dispos. (2005) [Pubmed]
  5. Effects of afloqualone on vestibular nystagmus and the lateral vestibular nucleus. Kudo, Y., Ishida, R. Jpn. J. Pharmacol. (1989) [Pubmed]
  6. Metabolism of afloqualone, a new centrally acting muscle relaxant, in monkeys and dogs. Otsuka, M., Furuuchi, S., Usuki, S., Nitta, S., Harigaya, S. J. Pharmacobio-dyn. (1983) [Pubmed]
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