Disease relevance of Borogluconate

• Calcium was varied by infusing 4.7% solution of ethylenediaminetetra-acetic acid disodium salt to induce hypocalcemia, followed by treatment with calcium borogluconate [1].
• Despite treatment with antibiotics and calcium borogluconate 19 ewes died, more than 60 developed vaginal discharges and at lambing 94 ewes were barren [2].
• One of the clinical signs of ephemeral fever, a temporary paralysis reversible by treatment with calcium borogluconate, is similar to that in milk fever (parturient paresis), a disease of multiparous dairy cows [3].

High impact information on Borogluconate

• A further three ewes in the last two weeks of gestation were thyroparathyroidectomized and normal plasma calcium concentration maintained by an intravenous infusion of calcium borogluconate [4].
• Hypocalcaemia sufficient to produce sternal recumbency in a further four cows resulted in a highly significant fall in the mean arterial blood pressure, which returned to normal immediately after treatment with an intravenous infusion of 350 ml of 32.5 per cent calcium borogluconate [5].

Chemical compound and disease context of Borogluconate

• Hypocalcemia is treated best by administering intravenous calcium borogluconate solutions or oral CaCl2 gels [6].

References