Disease relevance of OCRYLATE

• CONCLUSIONS: Although further study will be necessary before this technique can be used in humans, our findings indicate that octyl 2-cyanoacrylate is superior to the cyanoacrylate adhesives used in the past in terms of adhesion and holding power; given its favorable toxicity profile, this product may offer interesting applications in the future [1].
• Use of octyl-2-cyanoacrylate in cleft lip repair [2].
• No allergic reactions, wound infections, or dehiscences occurred.The use of octyl-2-cyanoacrylate for the skin closure of primary and revision cleft lip repairs in both children and adults results in excellent cosmetic outcomes [3].

High impact information on OCRYLATE

• Use of octyl-2-cyanoacrylate for skin closure in facial plastic surgery [4].
• Primary and revision cleft lip repairs using octyl-2-cyanoacrylate [3].
• Octyl 2-cyanoacrylate for repair of peripheral nerve [5].
• METHODS: An encircling band of silicone, which is generally anchored to the sclera itself, was sutured in 36 rabbit eyes to three small silastic patches that had been glued to the sclera, at the level of the equator, using octyl 2-cyanoacrylate tissue adhesive [6].
• OBJECTIVE: To compare the surgical efficacy and wound-healing characteristics of the tissue adhesive octyl-2-cyanoacrylate (approved by the Food and Drug Administration) with traditional suture closure in upper blepharoplasty [7].

Biological context of OCRYLATE

• Efficacy of octyl-2-cyanoacrylate tissue glue in blepharoplasty. A prospective controlled study of wound-healing characteristics [7].

Analytical, diagnostic and therapeutic context of OCRYLATE

• The lower visual analog scale score represented a superior cosmetic outcome at 1 year with the octyl-2-cyanoacrylate as compared with sutures [4].
• One hundred and eleven patients underwent elective surgical procedures by the same surgeon using either octyl-2-cyanoacrylate or sutures for skin closure at the University of Illinois at Chicago. Most patients underwent excision of benign skin lesions with a mean wound size of 112 mm3 [4].
• Octyl-2-cyanoacrylate tissue adhesive in external dacryocystorhinostomy [8].
• Octyl 2-cyanoacrylate tissue adhesive in experimental scleral buckling [6].
• Toxic effects in cell culture of a new long-chained octyl-2-cyanoacrylate tissue adhesive are compared with those of short-chained ethyl-2- and butyl-2-cyanoacrylates [9].

References