The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Wound Infection

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Wound Infection


High impact information on Wound Infection


Chemical compound and disease context of Wound Infection

  • A short six-dose course of metronidazole significantly reduces the wound-infection rate in patients over the age of 12 undergoing emergency appendicectomy [11].
  • The wound-infection rate after abdominal operations was compared in 113 patients randomly allocated to an untreated control group, a group receiving preoperative lincomycin and tobramycin, or a group receiving local instillation of povidone-iodine [12].
  • However, for surgical procedures lasting more than 4 hours, 5 of 14 patients (37.5%) receiving cefoxitin developed a wound infection v 0 of 13 patients receiving erythromycin-neomycin-cefazolin (p less than .05) [13].
  • Despire poor bile levels, gentamicin was associated with a significant reduction of wound infection from 22% to 6% and septicaemia from 14% to 2% compared with controls [14].
  • The efficacy of cefoxitin, a perioperative parenteral antibiotic, combined with mechanical bowel preparation and oral antibiotics to prevent wound infections and other septic complications in patients undergoing elective colorectal operations, was examined in a prospective randomized study [15].

Biological context of Wound Infection


Anatomical context of Wound Infection


Gene context of Wound Infection


Analytical, diagnostic and therapeutic context of Wound Infection


  1. Mycobacterium chelonae wound infections after plastic surgery employing contaminated gentian violet skin-marking solution. Safranek, T.J., Jarvis, W.R., Carson, L.A., Cusick, L.B., Bland, L.A., Swenson, J.M., Silcox, V.A. N. Engl. J. Med. (1987) [Pubmed]
  2. Extracellular fibrinogen-binding protein, Efb, from Staphylococcus aureus blocks platelet aggregation due to its binding to the alpha-chain. Palma, M., Shannon, O., Quezada, H.C., Berg, A., Flock, J.I. J. Biol. Chem. (2001) [Pubmed]
  3. Enhancement of dendritic cell production by fms-like tyrosine kinase-3 ligand increases the resistance of mice to a burn wound infection. Toliver-Kinsky, T.E., Cui, W., Murphey, E.D., Lin, C., Sherwood, E.R. J. Immunol. (2005) [Pubmed]
  4. Hepatectomy for hepatocellular carcinoma: toward zero hospital deaths. Fan, S.T., Lo, C.M., Liu, C.L., Lam, C.M., Yuen, W.K., Yeung, C., Wong, J. Ann. Surg. (1999) [Pubmed]
  5. Effect of single-dose prophylactic ampicillin and sulbactam on wound infection after tension-free inguinal hernia repair with polypropylene mesh: the randomized, double-blind, prospective trial. Yerdel, M.A., Akin, E.B., Dolalan, S., Turkcapar, A.G., Pehlivan, M., Gecim, I.E., Kuterdem, E. Ann. Surg. (2001) [Pubmed]
  6. Doxycycline in abdominal surgery. Klein, R.A., Busch, D.F., Wilson, S.E., Flora, D.J., Finegold, S.M. JAMA (1977) [Pubmed]
  7. Randomised controlled trial of single-dose antibiotic prophylaxis in surgical treatment of closed fractures: the Dutch Trauma Trial. Boxma, H., Broekhuizen, T., Patka, P., Oosting, H. Lancet (1996) [Pubmed]
  8. Successful substitution of rectal metronidazole administration for intravenous use. McLean, A., Ioannides-Demos, L., Somogyi, A., Tong, N., Spicer, J. Lancet (1983) [Pubmed]
  9. Povidone iodine in wound infection. Gilmore, O.J. Lancet (1977) [Pubmed]
  10. Antibiotic prophylaxis for percutaneous endoscopic gastrostomy. A prospective, randomized, double-blind clinical trial. Jain, N.K., Larson, D.E., Schroeder, K.W., Burton, D.D., Cannon, K.P., Thompson, R.L., DiMagno, E.P. Ann. Intern. Med. (1987) [Pubmed]
  11. Clinical and economic consequences of wound sepsis after appendicectomy and their modification by metronidazole or povidone iodine. Foster, G.E., Bourke, J.B., Bolwell, J., Doran, J., Balfour, T.W., Holliday, A., Hardcastle, J.D., Marshall, D.J. Lancet (1981) [Pubmed]
  12. Prevention of wound infection in abdominal operations by peroperative antibiotics or povidone-iodine. A controlled trial. Galland, R.B., Saunders, J.H., Mosley, J.G., Darrell, J.H. Lancet (1977) [Pubmed]
  13. Cefoxitin versus erythromycin, neomycin, and cefazolin in colorectal operations. Importance of the duration of the surgical procedure. Kaiser, A.B., Herrington, J.L., Jacobs, J.K., Mulherin, J.L., Roach, A.C., Sawyers, J.L. Ann. Surg. (1983) [Pubmed]
  14. Antibiotics in biliary disease: the relative importance of antibiotic concentrations in the bile and serum. Keighley, M.R., Drysdale, R.B., Quoraishi, A.H., Burdon, D.W., Alexander-Willians, J. Gut (1976) [Pubmed]
  15. Addition of parenteral cefoxitin to regimen of oral antibiotics for elective colorectal operations. A randomized prospective study. Schoetz, D.J., Roberts, P.L., Murray, J.J., Coller, J.A., Veidenheimer, M.C. Ann. Surg. (1990) [Pubmed]
  16. Use of peroperative cefoxitin to prevent infection after colonic and rectal surgery. Hoffmann, C.E., McDonald, P.J., Watts, J.M. Ann. Surg. (1981) [Pubmed]
  17. Randomized prospective double-blind trial in healing chronic diabetic foot ulcers. CT-102 activated platelet supernatant, topical versus placebo. Steed, D.L., Goslen, J.B., Holloway, G.A., Malone, J.M., Bunt, T.J., Webster, M.W. Diabetes Care (1992) [Pubmed]
  18. Wound prophylaxis in thoracic surgery: a new approach. Walker, W.S., Faichney, A., Raychaudhury, T., Prescott, R.J., Calder, M.A., Sang, C.T., Cameron, E.W., Walbaum, P.R. Thorax (1984) [Pubmed]
  19. Lack of the extracellular 19-kilodalton fibrinogen-binding protein from Staphylococcus aureus decreases virulence in experimental wound infection. Palma, M., Nozohoor, S., Schennings, T., Heimdahl, A., Flock, J.I. Infect. Immun. (1996) [Pubmed]
  20. Stimulation of hematopoiesis by the Fms-like tyrosine kinase 3 ligand restores bacterial induction of Th1 cytokines in thermally injured mice. Toliver-Kinsky, T.E., Lin, C.Y., Herndon, D.N., Sherwood, E.R. Infect. Immun. (2003) [Pubmed]
  21. Penetration of cefoperazone into surgical wound drainage in patients undergoing head and neck surgery. Muder, R.R., Yu, V.L., Johnson, J., Thearle, P., Lyon, J., Diven, W. Antimicrob. Agents Chemother. (1984) [Pubmed]
  22. Prospective randomized trial of Ivalon sponge versus sutured rectopexy for full-thickness rectal prolapse. Novell, J.R., Osborne, M.J., Winslet, M.C., Lewis, A.A. The British journal of surgery. (1994) [Pubmed]
  23. Determinants of wound infection incidence after isolated coronary artery bypass surgery in patients randomized to receive prophylactic cefuroxime or cefazolin. Conklin, C.M., Gray, R.J., Neilson, D., Wong, P., Tomita, D.K., Matloff, J.M. Ann. Thorac. Surg. (1988) [Pubmed]
  24. Analysis of brain abscess after penetrating craniocerebral injuries in Vietnam. Rish, B.L., Caveness, W.F., Dillon, J.D., Kistler, J.P., Mohr, J.P., Weiss, G.H. Neurosurgery (1981) [Pubmed]
  25. The beneficial effect of granulocyte colony-stimulating factor (G-CSF) in combination with gentamicin on survival after Pseudomonas burn wound infection. Silver, G.M., Gamelli, R.L., O'Reilly, M. Surgery (1989) [Pubmed]
  26. Hemorrhage decreases macrophage inflammatory protein 2 and interleukin-6 release: a possible mechanism for increased wound infection. Angele, M.K., Knöferl, M.W., Schwacha, M.G., Ayala, A., Bland, K.I., Cioffi, W.G., Josephson, S.L., Chaudry, I.H. Ann. Surg. (1999) [Pubmed]
  27. Preincisional intravenous pentoxifylline attenuating perioperative cytokine response, reducing morphine consumption, and improving recovery of bowel function in patients undergoing colorectal cancer surgery. Lu, C.H., Chao, P.C., Borel, C.O., Yang, C.P., Yeh, C.C., Wong, C.S., Wu, C.T. Anesth. Analg. (2004) [Pubmed]
  28. Dose dependency of granulocyte-macrophage colony stimulating factor for improving survival following burn wound infection. O'Reilly, M., Silver, G.M., Gamelli, R.L., Davis, J.H., Hebert, J.C. The Journal of trauma. (1994) [Pubmed]
  29. Effect of basic fibroblast growth factor on wound healing in healing-impaired animal models. Okumura, M., Okuda, T., Nakamura, T., Yajima, M. Arzneimittel-Forschung. (1996) [Pubmed]
  30. Bacterial sepsis and chemokines. Kobayashi, M., Tsuda, Y., Yoshida, T., Takeuchi, D., Utsunomiya, T., Takahashi, H., Suzuki, F. Current drug targets. (2006) [Pubmed]
  31. Tube gastrostomy. Techniques and complications. Shellito, P.C., Malt, R.A. Ann. Surg. (1985) [Pubmed]
  32. Transient cutaneous adenoviral gene therapy with human host defense peptide hCAP-18/LL-37 is effective for the treatment of burn wound infections. Jacobsen, F., Mittler, D., Hirsch, T., Gerhards, A., Lehnhardt, M., Voss, B., Steinau, H.U., Steinstraesser, L. Gene Ther. (2005) [Pubmed]
  33. Ornidazole and anaerobic bacteria: in vitro sensitivity and effects on wound infections after appendectomy. Palmu, A., Renkonen, O.V., Aromaa, U. J. Infect. Dis. (1979) [Pubmed]
  34. Efficacy of sulbactam alone and in combination with ampicillin in nosocomial infections caused by multiresistant Acinetobacter baumannii. Corbella, X., Ariza, J., Ardanuy, C., Vuelta, M., Tubau, F., Sora, M., Pujol, M., Gudiol, F. J. Antimicrob. Chemother. (1998) [Pubmed]
  35. Tinidazole in the prevention of post-operative wound infection after hysterectomy. Janssens, D., Peeters, N., Snauwaert, E., Cattersel, B. J. Antimicrob. Chemother. (1982) [Pubmed]
WikiGenes - Universities