Chemical Compound Review:
CHEMBL447065 2-bromoprop-2-enal
Synonyms:
CCRIS 1618, AG-D-95304, ACMC-20ao1z, LS-14611, CTK4C6108, ...
- Lack of mammalian mutagenicity of the potent bacterial mutagen tris(2,3-dibromopropyl) phosphate and its metabolite 2-bromoacrolein. van Beerendonk, G.J., Klein, J.C., Tijdens, R.B., Lichtenauer-Kaligis, E.G., Tasseron-de Jong, J.G., Meerman, J.H. Mutat. Res. (1998)
- Formation of cyclic 1,N2-propanodeoxyguanosine and thymidine adducts in the reaction of the mutagen 2-bromoacrolein with calf thymus DNA. Meerman, J.H., Smith, T.R., Pearson, P.G., Meier, G.P., Nelson, S.D. Cancer Res. (1989)
- Genotoxicity of the flame retardant tris(2,3-dibromopropyl)phosphate in the rat and Drosophila: effects of deuterium substitution. van Beerendonk, G.J., Nivard, M.J., Vogel, E.W., Nelson, S.D., Meerman, J.H. Carcinogenesis (1994)
- Identification of N-acetylcysteine conjugates of 1,2-dibromo-3-chloropropane: evidence for cytochrome P450 and glutathione mediated bioactivation pathways. Weber, G.L., Steenwyk, R.C., Nelson, S.D., Pearson, P.G. Chem. Res. Toxicol. (1995)
- Characterization of 2'-deoxycytidine and 2'-deoxyuridine adducts formed in reactions with acrolein and 2-bromoacrolein. Chenna, A., Iden, C.R. Chem. Res. Toxicol. (1993)
- Genotoxicity of 2-halosubstituted enals and 2-chloroacrylonitrile in the Ames test and the SOS-chromotest. Eder, E., Deininger, C., Deininger, D., Weinfurtner, E. Mutat. Res. (1994)
- Activation mechanism of tris(2,3-dibromopropyl)phosphate to the potent mutagen, 2-bromoacrolein. Nelson, S.D., Omichinski, J.G., Iyer, L., Gordon, W.P., Soderlund, E.J., Dybing, E. Biochem. Biophys. Res. Commun. (1984)