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Chemical Compound Review

AC1MHZNB     2,4,6,8- tetramethyloctacosanoic acid

Synonyms: AGN-PC-00RXXW, 5691-98-5, 2,4,6,8-Tetramethyloctacosanoic acid, Octacosanoic acid, 2,4,6,8-tetramethyl-
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Disease relevance of Mycocerosic acid


High impact information on Mycocerosic acid


Chemical compound and disease context of Mycocerosic acid


  1. Targeted replacement of the mycocerosic acid synthase gene in Mycobacterium bovis BCG produces a mutant that lacks mycosides. Azad, A.K., Sirakova, T.D., Rogers, L.M., Kolattukudy, P.E. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  2. Methylmalonyl coenzyme A selectivity of cloned and expressed acyltransferase and beta-ketoacyl synthase domains of mycocerosic acid synthase from Mycobacterium bovis BCG. Fernandes, N.D., Kolattukudy, P.E. J. Bacteriol. (1997) [Pubmed]
  3. Use of selected ion monitoring for detection of tuberculostearic and C32 mycocerosic acid in mycobacteria and in five-day-old cultures of sputum specimens from patients with pulmonary tuberculosis. Larsson, L., Mårdh, P., Odham, G., Westerdahl, G. Acta pathologica et microbiologica Scandinavica. Section B, Microbiology. (1981) [Pubmed]
  4. Dissecting the mechanism and assembly of a complex virulence mycobacterial lipid. Trivedi, O.A., Arora, P., Vats, A., Ansari, M.Z., Tickoo, R., Sridharan, V., Mohanty, D., Gokhale, R.S. Mol. Cell (2005) [Pubmed]
  5. Fatty acid biosynthesis in Mycobacterium tuberculosis var. bovis Bacillus Calmette-Guérin. Purification and characterization of a novel fatty acid synthase, mycocerosic acid synthase, which elongates n-fatty acyl-CoA with methylmalonyl-CoA. Rainwater, D.L., Kolattukudy, P.E. J. Biol. Chem. (1985) [Pubmed]
  6. Open reading frame 3, which is adjacent to the mycocerosic acid synthase gene, is expressed as an acyl coenzyme A synthase in Mycobacterium bovis BCG. Fitzmaurice, A.M., Kolattukudy, P.E. J. Bacteriol. (1997) [Pubmed]
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