The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

Table of contents

About

Terms

 

Chemical Compound Review: 

N-hexyl-6-     N-hexylhexanediamide

Synonyms: AC1MHUX2, AG-H-69092, CTK5G7431, AC1L1V11, 9011-55-6, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of N-hexylhexanediamide

  • Of the inline filters tested, only the one composed of Posidyne Nylon 66 was able to retain E. coli endotoxin for 96 hours [1].
 

High impact information on N-hexylhexanediamide

  • This study evaluated the effects of crystalline polyamide (Nylon-66), poly(ethylene-co-vinyl alcohol) (PEVA), and poly(vinylidene fluoride) (PVDF) polymers with nonporous and porous morphologies on the ability of monocytes to adhere and subsequently activate to produce IL-1beta, IL-6, and tumor necrosis factor alpha [2].
  • Detection by 125I-cationized cytochrome c of proteoglycans and glycosaminoglycans immobilized on unmodified and on positively charged nylon 66 [3].
  • Specimens of 14C-labeled poly(ethylene terephthalate), nylon 66, and poly(methyl methacrylate) have been synthesized and exposed, in vitro, to a number of enzyme solutions [4].
  • The 0.2 microm positively charged nylon 66 filter and the 0.2 microm nylon 66 filter, but not the PES filter (1.2 and 0.2 microm), decreased the concentrations of amphotericin B in the filtered fluid by 100% within 1 h and by 66% within 24 h after the start of filtration, respectively [5].
  • Under the test conditions, the Nylon 66 membranes provided total retention of P. diminuta [6].
 

Biological context of N-hexylhexanediamide

  • Up to 9000 U of enzyme activity was immobilized onto 2000 cm2 of a nylon 6 membrane where 1 U is the amount of enzyme necessary to catalyze the hydrolysis of 1.0 mumol of paraoxon/min at 25 degrees C. The nylon 66 membrane-bound phosphotriesterase was characterized kinetically where the apparent Km value for the immobilized enzyme was 0.35 mM [7].
 

Analytical, diagnostic and therapeutic context of N-hexylhexanediamide

  • Cyclic polyamide oligomers extracted from nylon 66 membrane filter disks as a source of contamination in liquid chromatography/mass spectrometry [8].
  • Immobilization on Nylon 66 appears to allow a relative freedom of interaction between PGs or GAGs and 125I-cationized cytochrome c, but a more restricted reaction was observed when PGs and GAGs were immobilized to positively charged Nylon 66 [3].

References

  1. Bacterial endotoxin retention by inline intravenous filters. Baumgartner, T.G., Schmidt, G.L., Thakker, K.M., Sitren, H.S., Cerda, J.J., Mahaffey, S.M., Copeland, E.M. American journal of hospital pharmacy. (1986) [Pubmed]
  2. Human monocyte adhesion and activation on crystalline polymers with different morphology and wettability in vitro. Young, T.H., Lin, D.T., Chen, L.Y. J. Biomed. Mater. Res. (2000) [Pubmed]
  3. Detection by 125I-cationized cytochrome c of proteoglycans and glycosaminoglycans immobilized on unmodified and on positively charged nylon 66. Heimer, R., Molinaro, L., Sampson, P.M. Anal. Biochem. (1987) [Pubmed]
  4. The enzymatic degradation of polymers in vitro. Smith, R., Oliver, C., Williams, D.F. J. Biomed. Mater. Res. (1987) [Pubmed]
  5. Evaluation of the in-line filters for the intravenous infusion of amphotericin B fluid. Hirakawa, M., Makino, K., Nakashima, K., Kataoka, Y., Oishi, R. Journal of clinical pharmacy and therapeutics. (1999) [Pubmed]
  6. Microbial retention characteristics of 0.2-microns-rated nylon membrane filters during filtration of high viscosity fluids at high differential pressure and varied temperatures. Aranha, H., Meeker, J. PDA journal of pharmaceutical science and technology / PDA. (1995) [Pubmed]
  7. Detoxification of organophosphate pesticides using a nylon based immobilized phosphotriesterase from Pseudomonas diminuta. Caldwell, S.R., Raushel, F.M. Appl. Biochem. Biotechnol. (1991) [Pubmed]
  8. Cyclic polyamide oligomers extracted from nylon 66 membrane filter disks as a source of contamination in liquid chromatography/mass spectrometry. Tran, J.C., Doucette, A.A. J. Am. Soc. Mass Spectrom. (2006) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities