Disease relevance of Piridoxylate

• So, it seems necessary to monitor the serum creatinine level, especially in the elderly, during piridoxilate therapy and to avoid high vitamin C intakes in patients under such treatment to prevent development of renal insufficiency [1].
• These findings suggest a protective action of piridoxilate against hypoxia which may be attributable to rearrangement of the myocardial metabolism [2].

Psychiatry related information on Piridoxylate

• This conclusion was also confirmed by psychometric tests demonstrating a greater improvement in attention, concentration, attention variability, tapping, visual and numerical memory, and aftereffect (Archimedean spiral) in the piridoxilate than in the placebo group [3].

High impact information on Piridoxylate

• Effects of piridoxilate, a glyoxylic acid derivative, on the energy metabolism of the heart [2].
• After pretreatment of the preparation with piridoxilate, the depression of redox potential and the increase in NADH fluorescence produced by N2 gas inhalation or by NaCN infusion were clearly reduced [2].

Analytical, diagnostic and therapeutic context of Piridoxylate

• Spectral analysis of the EEG showed an increase in alpha and a decrease in fast beta activities in both groups, while delta activity was attenuated only in the piridoxilate-treated group [3].

References