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Chemical Compound Review

AC1LAQM7     4-amino-1-[(1R,4S,5R)-4,5- dihydroxy-3...

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Disease relevance of Cyclopentenylcytosine


High impact information on Cyclopentenylcytosine


Anatomical context of Cyclopentenylcytosine


Associations of Cyclopentenylcytosine with other chemical compounds


  1. Resistance to cyclopentenylcytosine in murine leukemia L1210 cells. Zhang, H., Cooney, D.A., Zhang, M.H., Ahluwalia, G., Ford, H., Johns, D.G. Cancer Res. (1993) [Pubmed]
  2. A mutant of Sindbis virus which is able to replicate in cells with reduced CTP makes a replicase/transcriptase with a decreased Km for CTP. Li, M.L., Lin, Y.H., Simmonds, H.A., Stollar, V. J. Virol. (2004) [Pubmed]
  3. Effect of CTP synthetase regulation by CTP on phospholipid synthesis in Saccharomyces cerevisiae. Ostrander, D.B., O'Brien, D.J., Gorman, J.A., Carman, G.M. J. Biol. Chem. (1998) [Pubmed]
  4. Cyclopentenylcytosine triphosphate. Formation and inhibition of CTP synthetase. Kang, G.J., Cooney, D.A., Moyer, J.D., Kelley, J.A., Kim, H.Y., Marquez, V.E., Johns, D.G. J. Biol. Chem. (1989) [Pubmed]
  5. Broad-spectrum antiviral and cytocidal activity of cyclopentenylcytosine, a carbocyclic nucleoside targeted at CTP synthetase. De Clercq, E., Murase, J., Marquez, V.E. Biochem. Pharmacol. (1991) [Pubmed]
  6. Sensitizing human colon carcinoma HT-29 cells to cisplatin by cyclopentenylcytosine, in vitro and in vivo. Gharehbaghi, K., Szekeres, T., Yalowitz, J.A., Fritzer-Szekeres, M., Pommier, Y.G., Jayaram, H.N. Life Sci. (2000) [Pubmed]
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