The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Dorevan     1-[10-(2-dimethylaminopropyl) phenothiazin...

Synonyms: Phenoctyl, Largon, Propiomazina, propiomazine, Propiomazinum, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of CB 1678

  • We have now investigated the effects of propiomazine, a phenothiazine hypnotic, in a double-blind randomized cross-over study of oxygen saturation and apneas during sleep and other sleep variables in 12 non-obese hypoxemic but clinically stable theophylline-treated COPD patients (PaO2 8.1 kPa, PaCO2 5.6 kPa, FEV1 31% of predicted value) [1].

Psychiatry related information on CB 1678


High impact information on CB 1678


Associations of CB 1678 with other chemical compounds


Analytical, diagnostic and therapeutic context of CB 1678


  1. Effects of single doses of propiomazine, a phenothiazine hypnotic, on sleep and oxygenation in patients with stable chronic obstructive pulmonary disease. Midgren, B., Hansson, L., Ahlmann, S., Elmqvist, D. Respiration; international review of thoracic diseases. (1990) [Pubmed]
  2. Physostigmine reversal of sedation in parturients. Smith, D.B., Clark, R.B., Stephens, S.R., Sherman, R.L., Hyde, M.L. Anesth. Analg. (1976) [Pubmed]
  3. A comparison of zopiclone and propiomazine as hypnotics in outpatients: a multicentre, double-blind, randomized, parallel-group comparison of zopiclone and propiomazine in insomniacs. Dehlin, O., Bengtsson, C., Rubin, B. Current medical research and opinion. (1997) [Pubmed]
  4. Effect of propiomazine on plasma prolactin in the rat: counteraction by L-dopa. Fayez, M., Ahmed, H.H., Quadri, S.K. Proc. Soc. Exp. Biol. Med. (1985) [Pubmed]
  5. Physostigmine's effect on diminished fetal heart rate variability caused by scopolamine, meperidine and propiomazine. Boehm, F.H., Egilmez, A., Smith, B.E. Journal of perinatal medicine. (1977) [Pubmed]
  6. Determination of propiomazine and its N-demethyl metabolite in plasma by gas chromatography with alkali flame ionization detection. Hartvig, P., Ahs, U., Wickström, G. J. Chromatogr. (1980) [Pubmed]
  7. Effects of propiomazine on the EEG sleep of normal subjects. Almqvist, M., Liljenberg, B., Hetta, J., Rimon, R., Hambert, G., Roos, B.E. Pharmacol. Toxicol. (1987) [Pubmed]
  8. Determination of propiomazine in rat plasma by direct injection on coupled liquid chromatography columns with electrochemical detection. Benkestock, K. J. Chromatogr. B Biomed. Sci. Appl. (1997) [Pubmed]
WikiGenes - Universities