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Chemical Compound Review

Flurfamide     N-diaminophosphoryl-4-fluoro- benzamide

Synonyms: Flurofamida, Flurofamide, Flurofamine, Flurofamidum, Tocris-0478, ...
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Disease relevance of EU-4534


High impact information on EU-4534


Anatomical context of EU-4534

  • Flurofamide was then evaluated in a system comparable to the procedure for semen extension with respect to temperature, time and dilution [4].

Analytical, diagnostic and therapeutic context of EU-4534


  1. Structure-activity relationship of omeprazole and analogues as Helicobacter pylori urease inhibitors. Kühler, T.C., Fryklund, J., Bergman, N.A., Weilitz, J., Lee, A., Larsson, H. J. Med. Chem. (1995) [Pubmed]
  2. Flurofamide: a potent inhibitor of bacterial urease with potential clinical utility in the treatment of infection induced urinary stones. Millner, O.E., Andersen, J.A., Appler, M.E., Benjamin, C.E., Edwards, J.G., Humphrey, D.T., Shearer, E.M. J. Urol. (1982) [Pubmed]
  3. Marked reduction of Helicobacter pylori-induced gastritis by urease inhibitors, acetohydroxamic acid and flurofamide, in Mongolian gerbils. Ohta, T., Shibata, H., Kawamori, T., Iimuro, M., Sugimura, T., Wakabayashi, K. Biochem. Biophys. Res. Commun. (2001) [Pubmed]
  4. The failure of flurofamide to control ureaplasma in bovine semen. Truscott, R.B., Brown, C. Can. J. Vet. Res. (1986) [Pubmed]
  5. Inhibition of the growth of Ureaplasma urealyticum by a new urease inhibitor, flurofamide. Kenny, G.E. The Yale journal of biology and medicine. (1983) [Pubmed]
  6. Immunological and molecular characterization of Helicobacter felis urease. Gootz, T.D., Perez-Perez, G.I., Clancy, J., Martin, B.A., Tait-Kamradt, A., Blaser, M.J. Infect. Immun. (1994) [Pubmed]
  7. Effect of the metabolism of urea on the acidifying activity of Streptococcus thermophilus. Pernoud, S., Fremaux, C., Sepulchre, A., Corrieu, G., Monnet, C. J. Dairy Sci. (2004) [Pubmed]
  8. Virulence of ureaplasmal urease for mice. Ligon, J.V., Kenny, G.E. Infect. Immun. (1991) [Pubmed]
  9. Investigation into the inhibitory effect of flurofamide on animal ureaplasmas and its use in the treatment of ureaplasma-infected sheep. Ball, H.J., McCaughey, W.J. J. Vet. Pharmacol. Ther. (1986) [Pubmed]
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