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Chemical Compound Review

Assure     ethyl 2-[4-(6-chloroquinoxalin-2...

Synonyms: Pilot, Targa, Xylofop-ethyl, Quinofop-ethyl, SureCN30406, ...
 
 
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Disease relevance of QUIZALOFOP-ETHYL

  • Using murine leukemia L1210 cells in culture, we found the chiral R(+) form of XK469 to be substantially more cytotoxic than the S(-) form, while the herbicide analog 'Assure' was essentially inactive [1].
  • Evaluation of rapid test Assure Helicobacter pylori for diagnosis of H. pylori in pediatric population [2].
 

High impact information on QUIZALOFOP-ETHYL

  • XK469 (NSC 697887; (+/-)-2-[4-(7-chloro-2-quinoxaliny)oxy]phenoxy propionic acid), an analog of the herbicide Assure, which possesses antitumor activity, especially against murine solid tumors and human xenografts, has recently been found to be the first topoisomerase IIbeta poison [3].
  • METHODS: Four adhesives (Transbond XT primer [3M Unitek, Monrovia, Calif], Transbond Plus self-etch primer [3M Unitek], Assure hydrophilic primer [Reliance, Itasca, Ill], and SmartBond cyanoacrylate [Gestenco, Gothenburg, Sweden]) were used to bond stainless steel maxillary central incisor brackets to 120 bovine permanent mandibular incisors [4].
  • The purpose of this study was to investigate whether Transbond XT with MIP and Assure were affected by light curing the primers before contamination with blood or saliva [5].
  • The values of the Assure primer and adhesive were less than the MIP primer and its respective adhesive; however, the hydrophilic Assure adhesive resin applied to a saliva-contaminated surface had acceptable bond strength [6].
  • This study compared the shear bond strengths of 2 lightcured hydrophilic bonding systems, Transbond XT with MIP (3M/Unitek, Monrovia, Calif) and Assure (Reliance Orthodontics, Itasca, Ill) with a hydrophobic bonding system, Transbond XT with XT primer (3M/Unitek) [7].
 

Gene context of QUIZALOFOP-ETHYL

  • The objective of this in vitro bonding study was to evaluate the effectiveness of 2 moisture-insensitive primers, Assure (Reliance Orthodontic Products, Itasca, Ill) and MIP (3M Unitek, Monrovia, Calif) compared with a control hydrophobic primer, Transbond XT (3M Unitek) [6].
 

Analytical, diagnostic and therapeutic context of QUIZALOFOP-ETHYL

References

  1. Pro-apoptotic interactions between XK469 and the peripheral benzodiazepine receptor. Kessel, D., Horwitz, J.P. Cancer Lett. (2001) [Pubmed]
  2. Evaluation of rapid test Assure Helicobacter pylori for diagnosis of H. pylori in pediatric population. Pelerito, A., Oleastro, M., Lopes, A.I., Ramalho, P., Cabral, J., Monteiro, L. J. Microbiol. Methods (2006) [Pubmed]
  3. Chiral pharmacokinetics and inversion of enantiomers of a new quinoxaline topoisomerase IIbeta poison in the rat. Zheng, H., Jiang, C., Chiu, M.H., Covey, J.M., Chan, K.K. Drug Metab. Dispos. (2002) [Pubmed]
  4. Effect of blood and saliva contamination on shear bond strength of brackets bonded with 4 adhesives. Oztoprak, M.O., Isik, F., Sayinsu, K., Arun, T., Aydemir, B. American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics (2007) [Pubmed]
  5. Light curing the primer-beneficial when working in problem areas? Sayinsu, K., Isik, F., Sezen, S., Aydemir, B. The Angle orthodontist. (2006) [Pubmed]
  6. Bond strength comparison of moisture-insensitive primers. Schaneveldt, S., Foley, T.F. American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics. (2002) [Pubmed]
  7. The effect of saliva on shear bond strengths of hydrophilic bonding systems. Webster, M.J., Nanda, R.S., Duncanson, M.G., Khajotia, S.S., Sinha, P.K. American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics. (2001) [Pubmed]
  8. Femoral anastomotic aneurysms. Hollier, L.H., Batson, R.C., Cohn, I. Ann. Surg. (1980) [Pubmed]
  9. Conception rates in clomiphene citrate cycles with and without hormone supplementation: a pilot study. Elkind-Hirsch, K.E., Darensbourg, C., Creasy, G., Gipe, D. Current medical research and opinion. (2005) [Pubmed]
 
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