The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Celastraceae


High impact information on Celastraceae


Biological context of Celastraceae


Associations of Celastraceae with chemical compounds


Gene context of Celastraceae

  • Antidiabetic principles of natural medicines. IV. Aldose reductase and qlpha-glucosidase inhibitors from the roots of Salacia oblonga Wall. (Celastraceae): structure of a new friedelane-type triterpene, kotalagenin 16-acetate [13].
  • TLC autographic assay revealed, in the EtOAc extract obtained from leaves and root bark of Maytenus aquifolium (Celastraceae), the presence of fi ve compounds exhibiting antioxidant properties towards beta-carotene [14].
  • Thirty four crude extracts of Panamanian plants, from nine species of Celastraceae and Lamiaceae, were assayed for xanthine oxidase (XO) inhibitory activity [15].
  • Maytenus ilicifolia (Celastraceae) is a native plant from Tropical Atlantic Forest (Mata Atlântica, Brazil) called 'espinheira-santa'. This plant is traditionally used as anti-inflammatory, analgesic and antiulcerogenic [16].


  1. Involvement of NF-kappaB and c-myc signaling pathways in the apoptosis of HL-60 cells induced by alkaloids of Tripterygium hypoglaucum (levl.) Hutch. Zhuang, W.J., Fong, C.C., Cao, J., Ao, L., Leung, C.H., Cheung, H.Y., Xiao, P.G., Fong, W.F., Yang, M.S. Phytomedicine (2004) [Pubmed]
  2. Celastraceae sesquiterpenes as a new class of modulators that bind specifically to human P-glycoprotein and reverse cellular multidrug resistance. Muñoz-Martínez, F., Lu, P., Cortés-Selva, F., Pérez-Victoria, J.M., Jiménez, I.A., Ravelo, A.G., Sharom, F.J., Gamarro, F., Castanys, S. Cancer Res. (2004) [Pubmed]
  3. Celastrol protects against MPTP- and 3-nitropropionic acid-induced neurotoxicity. Cleren, C., Calingasan, N.Y., Chen, J., Beal, M.F. J. Neurochem. (2005) [Pubmed]
  4. Inhibition of vascular endothelial growth factor expression and production by triptolide. Hu, K.B., Liu, Z.H., Liu, D., Li, L.S. Planta Med. (2002) [Pubmed]
  5. Spectral assignment and cytotoxicity of 22-hydroxytingenone from Glyptopetalum sclerocarpum. Bavovada, R., Blaskó, G., Shieh, H.L., Pezzuto, J.M., Cordell, G.A. Planta Med. (1990) [Pubmed]
  6. Kaurane and abietane diterpenoids from Tripterygium doianum (Celastraceae). Tanaka, N., Ooba, N., Duan, H., Takaishi, Y., Nakanishi, Y., Bastow, K., Lee, K.H. Phytochemistry (2004) [Pubmed]
  7. Nitric oxide-dependent vasorelaxation induced by extractive solutions and fractions of Maytenus ilicifolia Mart ex Reissek (Celastraceae) leaves. Rattmann, Y.D., Cipriani, T.R., Sassaki, G.L., Iacomini, M., Rieck, L., Marques, M.C., da Silva-Santos, J.E. Journal of ethnopharmacology. (2006) [Pubmed]
  8. Catalytic inhibition of topoisomerase IIalpha by demethylzeylasterone, a 6-oxophenolic triterpenoid from Kokoona zeylanica. Furbacher, T.R., Gunatilaka, A.A. J. Nat. Prod. (2001) [Pubmed]
  9. Quinone-methide triterpenes and salaspermic acid from Kokoona ochracea. Ngassapa, O., Soejarto, D.D., Pezzuto, J.M., Farnsworth, N.R. J. Nat. Prod. (1994) [Pubmed]
  10. Insecticidal activity of Maytenus species (Celastraceae) nortriterpene quinone methides against codling moth, Cydia pomonella (L.) (Lepidoptera: tortricidae). Avilla, J., Teixidò, A., Velázquez, C., Alvarenga, N., Ferro, E., Canela, R. J. Agric. Food Chem. (2000) [Pubmed]
  11. Biosynthesis of friedelane and quinonemethide triterpenoids is compartmentalized in Maytenus aquifolium and Salacia campestris. Corsino, J., de Carvalho, P.R., Kato, M.J., Latorre, L.R., Oliveira, O.M., Araújo, A.R., Bolzani, V.D., França, S.C., Pereira, A.M., Furlan, M. Phytochemistry (2000) [Pubmed]
  12. Novel quinone methides from Salacia kraussii with in vitro antimalarial activity. Figueiredo, J.N., Räz, B., Séquin, U. J. Nat. Prod. (1998) [Pubmed]
  13. Antidiabetic principles of natural medicines. IV. Aldose reductase and qlpha-glucosidase inhibitors from the roots of Salacia oblonga Wall. (Celastraceae): structure of a new friedelane-type triterpene, kotalagenin 16-acetate. Matsuda, H., Murakami, T., Yashiro, K., Yamahara, J., Yoshikawa, M. Chem. Pharm. Bull. (1999) [Pubmed]
  14. Antioxidant flavan-3-ols and flavonol glycosides from Maytenus aquifolium. Corsino, J., Silva, D.H., Zanoni, M.V., da Silva Bolzani, V., França, S.C., Pereira, A.M., Furlan, M. Phytotherapy research : PTR. (2003) [Pubmed]
  15. Xanthine oxidase inhibitory activity of some Panamanian plants from Celastraceae and Lamiaceae. González, A.G., Bazzocchi, I.L., Moujir, L., Ravelo, A.G., Correa, M.D., Gupta, M.P. Journal of ethnopharmacology. (1995) [Pubmed]
  16. Evaluation of antinociceptive, anti-inflammatory and antiulcerogenic activities of Maytenus ilicifolia. Jorge, R.M., Leite, J.P., Oliveira, A.B., Tagliati, C.A. Journal of ethnopharmacology. (2004) [Pubmed]
WikiGenes - Universities