The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

m-Coumarate     (E)-3-(3-hydroxyphenyl)prop- 2-enoic acid

Synonyms: PubChem8222, AC1LCUFW, CHEMBL98521, SureCN442408, H23007_ALDRICH, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of m-Hydroxycinnamic acid

  • E. coli K-12 also grew with 3-hydroxycinnamic acid as sole source of carbon; the ability of cells to oxidize cinnamic and 3-phenylpropionic acids, and hydroxylated derivatives, was investigated [1].
  • Expression in Salmonella typhimurium of the mhp genes alone or in combination with the hca cluster allowed the growth of the recombinant bacteria in 3-hydroxycinnamic acid (3HCI) and CI, respectively [2].

High impact information on m-Hydroxycinnamic acid


Biological context of m-Hydroxycinnamic acid


Anatomical context of m-Hydroxycinnamic acid


Associations of m-Hydroxycinnamic acid with other chemical compounds


Gene context of m-Hydroxycinnamic acid


  1. Catabolism of phenylpropionic acid and its 3-hydroxy derivative by Escherichia coli. Burlingame, R., Chapman, P.J. J. Bacteriol. (1983) [Pubmed]
  2. Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12. Díaz, E., Ferrández, A., García, J.L. J. Bacteriol. (1998) [Pubmed]
  3. Inhibitory effect of phenolic acids on the proliferation of 3T3-L1 preadipocytes in relation to their antioxidant activity. Hsu, C.L., Huang, S.L., Yen, G.C. J. Agric. Food Chem. (2006) [Pubmed]
  4. Determination of hydrogen peroxide scavenging activity of cinnamic and benzoic acids employing a highly sensitive peroxyoxalate chemiluminescence-based assay: structure-activity relationships. Mansouri, A., Makris, D.P., Kefalas, P. Journal of pharmaceutical and biomedical analysis. (2005) [Pubmed]
  5. Transepithelial transport of chlorogenic acid, caffeic acid, and their colonic metabolites in intestinal caco-2 cell monolayers. Konishi, Y., Kobayashi, S. J. Agric. Food Chem. (2004) [Pubmed]
  6. Microbial metabolites of ingested caffeic acid are absorbed by the monocarboxylic acid transporter (MCT) in intestinal Caco-2 cell monolayers. Konishi, Y., Kobayashi, S. J. Agric. Food Chem. (2004) [Pubmed]
  7. Structure-activity relationship of caffeic acid analogues on xanthine oxidase inhibition. Chan, W.S., Wen, P.C., Chiang, H.C. Anticancer Res. (1995) [Pubmed]
  8. Induction of G0/G1 arrest and apoptosis by 3-hydroxycinnamic acid in human cervix epithelial carcinoma (HeLa) cells. Chuang, J.Y., Tsai, Y.Y., Chen, S.C., Hsieh, T.J., Chung, J.G. In Vivo (2005) [Pubmed]
  9. Enzymatic hydroxylation of m-coumaric acid by mice liver hydroxylase. Bajaj, K.L., Singh, J., Chakravarti, P. Indian J. Exp. Biol. (1977) [Pubmed]
  10. Kinetic study on the slow inhibition of epidermis tyrosinase by m-coumaric acid. Cabanes, J., García-Carmona, F., García-Cánovas, F., Iborra, J.L., Lozano, J.A. Biochim. Biophys. Acta (1984) [Pubmed]
WikiGenes - Universities