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Chemical Compound Review

Pgem-II     (E)-7-(4-butyl-2,5-dioxo- 3,3a,4,6,7,7a...

Synonyms: Bicyclo-PGEM, DKDBCYPGE2, PGE2-M, AC1O5PK8, 74158-09-1
 
 
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Disease relevance of Pgem-II

  • The lack of change in bicyclo PGEM and PGFM in peripheral plasma would suggest a local transfer of PGs produced by injured tubal tissue to other parts of the tube and the uterus resulting in increased contractions and pelvic pain [1].
 

High impact information on Pgem-II

 

Analytical, diagnostic and therapeutic context of Pgem-II

  • Following the completion of the ultrasound examination, cordocentesis was performed and blood sent for estimation of bicyclo PGEM levels [6].

References

  1. Peripheral plasma levels of prostaglandin metabolites, cortisol and prolactin in women undergoing falope ring application and tubal cautery. Wolfe, W.M., Rao, C.V., McCracken, E., Demers, L.M., Huang, K.C., Tsueda, K. Prostaglandins, leukotrienes, and medicine. (1986) [Pubmed]
  2. Maternal plasma prostaglandin E2 metabolite levels during human pregnancy and parturition. Brennecke, S.P., Castle, B.M., Demers, L.M., Turnbull, A.C. British journal of obstetrics and gynaecology. (1985) [Pubmed]
  3. Plasma prostaglandin metabolites in human labor. Lackritz, R., Tulchinsky, D., Ryan, K.J., Levine, L. Am. J. Obstet. Gynecol. (1978) [Pubmed]
  4. Umbilical artery Doppler flow velocity waveforms and maternal prostaglandin E2 and F2 alpha metabolite concentrations during cervical ripening with prostaglandin E2. Fairlie, F.M., Lang, G.D., Greer, I.A., McLaren, M. Eur. J. Obstet. Gynecol. Reprod. Biol. (1990) [Pubmed]
  5. Peripheral prostaglandin metabolite levels in women undergoing therapeutic abortions in the first trimester with and without treatment with prostaglandin synthetase inhibitor. Wolfe, W.M., Rao, C.V., McCracken, E.M., Demers, L.M. Prostaglandins, leukotrienes, and medicine. (1987) [Pubmed]
  6. Fetal breathing movements and prostaglandin levels in pregnancies complicated by premature rupture of the membranes. Thompson, P.J., Greenough, A., Nicolaides, K.H. Journal of perinatal medicine. (1992) [Pubmed]
 
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