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Chemical Compound Review

perillaketone     1-(3-furyl)-4-methyl-pentan- 1-one

Synonyms: CHEMBL469753, Perilla ketone, SureCN4627614, CHEBI:617996, NSC-348407, ...
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Disease relevance of NSC 348407


High impact information on NSC 348407


Gene context of NSC 348407

  • Results: Both upward arrowP(LA) and PK were associated with statistically significant tracheal narrowing ( upward arrowP(LA): 20.3 +/- 0.6 to 15.1 +/- 0.9 mm; PK: 20.2 +/- 0.6 to 14.1 +/- 1.4 mm) [8].

Analytical, diagnostic and therapeutic context of NSC 348407


  1. Morphology of noncardiogenic pulmonary edema induced by Perilla ketone in sheep. Guerry-Force, M.L., Coggeshall, J., Snapper, J., Meyrick, B. Am. J. Pathol. (1988) [Pubmed]
  2. Perilla ketone toxicity: a chemical model for the study of equine restrictive lung disease. Breeze, R.G., Legreid, W.W., Bayly, W.M., Wilson, B.J. Equine Vet. J. (1984) [Pubmed]
  3. Reamed intramedullary femoral nailing after induction of an "ARDS-like" state in sheep: effect on clinically applicable markers of pulmonary function. Wolinsky, P.R., Banit, D., Parker, R.E., Shyr, Y., Snapper, J.R., Rutherford, E.J., Johnson, K.D. Journal of orthopaedic trauma. (1998) [Pubmed]
  4. Effect of cardiogenic and noncardiogenic pulmonary edema on histamine responsiveness in sheep. Snapper, J.R., Lefferts, P.L., Lu, W., Hwang, Y.S., Plitman, J.D. J. Appl. Physiol. (1998) [Pubmed]
  5. Perilla ketone increases endothelial cell monolayer permeability in vitro. Waters, C.M., Alexander, J.S., Harris, T.R., Haselton, F.R. J. Appl. Physiol. (1993) [Pubmed]
  6. The effects of selected bulky substituents on the pulmonary toxicity of 3-furyl ketones in mice. Wilson, W.C., Simon, J., Garst, J.E. J. Anim. Sci. (1990) [Pubmed]
  7. Species susceptibility to the pulmonary toxicity of 3-furyl isoamyl ketone (perilla ketone): in vivo support for involvement of the lung monooxygenase system. Garst, J.E., Wilson, W.C., Kristensen, N.C., Harrison, P.C., Corbin, J.E., Simon, J., Philpot, R.M., Szabo, R.R. J. Anim. Sci. (1985) [Pubmed]
  8. Effect of pulmonary edema on tracheal diameter. Snapper, J.R., Trochtenberg, D.S., Hwang, Y.S., Lefferts, P.L., Carroll, F.E., Worrell, J.A., O'Donnell, D.M. Respiration; international review of thoracic diseases. (1999) [Pubmed]
  9. Comparison of the pulmonary dysfunction caused by cardiogenic and noncardiogenic pulmonary edema. Bernard, G.R., Pou, N.A., Coggeshall, J.W., Carroll, F.E., Snapper, J.R. Chest (1995) [Pubmed]
  10. Neutral and DEAE dextrans as tracers for assessing lung microvascular barrier permeability and integrity. Sanders, J.R., Pou, N.A., Roselli, R.J. J. Appl. Physiol. (2002) [Pubmed]
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