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Chemical Compound Review:

PubChem10760 1,4-dichloro-2-nitro-benzene

Synonyms: AGN-PC-00GR5X, CHEMBL354761, SureCN358730, NSC-6294, CCRIS 3096, ...

Gallard, H. et al., Jin, Z.C. et al., Yamazaki, K. et al.

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Disease relevance of NSC6294

Plasmid pSK1002-mediated mutator effect and SOS response and SOS mutagenesis of 2,5-dichloronitrobenzol in Salmonella typhimurium [1].
Carcinogenicity and chronic toxicity of 1,4-dichloro-2-nitrobenzene in rats and mice by two years feeding [2].

High impact information on NSC6294

Besides, this study has proved SOS mutagenesis of 2,5-dichloronitrobenzol (2,5-DCNB) because of the dual indicator nature of pSK1002 [1].
The rates of degradation of 1,2,4-trichlorobenzene (TCB), 2,5-dichloronitrobenzene (DCNB), diuron and isoproturon by Fe(II)/H2O2 and Fe(III)/H2O2 have been investigated in dilute aqueous solution ([Organic compound]0 approximately 1 microM, at 25.0 +/- 0.2 degrees C and pH < or = 3) [3].

References

Plasmid pSK1002-mediated mutator effect and SOS response and SOS mutagenesis of 2,5-dichloronitrobenzol in Salmonella typhimurium. Jin, Z.C., Qian, J. Mutat. Res. (1991) [Pubmed]
Carcinogenicity and chronic toxicity of 1,4-dichloro-2-nitrobenzene in rats and mice by two years feeding. Yamazaki, K., Aiso, S., Matsumoto, M., Kano, H., Arito, H., Nagano, K., Yamamoto, S., Matsushima, T. Industrial health. (2006) [Pubmed]
Kinetics of oxidation of chlorobenzenes and phenyl-ureas by Fe(II)/H2O2 and Fe(III)/H2O2. Evidence of reduction and oxidation reactions of intermediates by Fe(II) or Fe(III). Gallard, H., De Laat, J. Chemosphere (2001) [Pubmed]

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