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Chemical Compound Review:

CHEBI:9347 2-[[(4R)-4- [(3R,5R,8S,9S,10S,13R,14S,17R) ...

Synonyms: AG-E-00814, CHEMBL2074584, AC1L2HNV, CTK0H7265, LMST05030015, ...

Baba, M. et al., Barbara, L. et al., Wildgrube, H.J. et al., Cantafora, A. et al., Kobayashi, N. et al., et al.

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Disease relevance of AIDS000472

Several cholic acid derivatives such as taurolithocholic acid, lithocholic acid 3-sulfate, taurolithocholic acid 3-sulfate, and glycolithocholic acid 3-sulfate were shown to inhibit selectively the replication of human immunodeficiency virus type 1 (HIV-1) in vitro [1].

High impact information on AIDS000472

In the liver of 27 male Wistar rats, the concentration of conjugated cholic acid was 41.3 (SD 11.7) nmol/g of tissue, of sulfoglycolithocholic acid 5.1 (SD 2.3) nmol/g of tissue [2].
A specific and sensitive radioimmunoassay for cholic, chenodeoxycholic, and lithocholic acid conjugates and for sulfolithocholylglycine was used to measure serum bile acids (BA) in infants and children [3].
Sulfolithocholylglycine was elevated in the sera of all 110 patients with hepatic disease [4].
The best conditions for the enzymatic hydrolysis with cholylglycine hydrolase of sulfolithocholylglycine and sulfolithocholyltaurine are described [5].

Analytical, diagnostic and therapeutic context of AIDS000472

A monoclonal antibody-based enzyme-linked immunosorbent assay of glycolithocholic acid sulfate in human urine for liver function test [6].

References

Selective activity of several cholic acid derivatives against human immunodeficiency virus replication in vitro. Baba, M., Schols, D., Nakashima, H., Pauwels, R., Parmentier, G., Meijer, D.K., De Clercq, E. J. Acquir. Immune Defic. Syndr. (1989) [Pubmed]
Radioimmunoassay of bile acids in tissue, bile, and urine. Wildgrube, H.J., Stockhausen, H., Metz, P., Mauritz, G., Mahdawi, R. Clin. Chem. (1983) [Pubmed]
Serum bile acids in newborns and children. Barbara, L., Lazzari, R., Roda, A., Aldini, R., Festi, D., Sama, C., Morselli, A.M., Collina, A., Bazzoli, F., Mazzella, G., Roda, E. Pediatr. Res. (1980) [Pubmed]
Levels of immunoreactive glycine-conjugated bile acids in health and hepatobiliary disease. Demers, L.M., Hepner, G.W. Am. J. Clin. Pathol. (1976) [Pubmed]
An improved gas-chromatographic method for the determination of sulfated and unsulfated bile acids in serum. Cantafora, A., Angelico, M., Attili, A.F., Ercoli, L., Capocaccia, L. Clin. Chim. Acta (1979) [Pubmed]
A monoclonal antibody-based enzyme-linked immunosorbent assay of glycolithocholic acid sulfate in human urine for liver function test. Kobayashi, N., Katsumata, H., Uto, Y., Goto, J., Niwa, T., Kobayashi, K., Mizuuchi, Y. Steroids (2002) [Pubmed]

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