Disease relevance of X-Pand

• We noted hand deformities characteristic of inflammatory arthritis in Jean-Baptiste-Camille Corot's Gipsy Girl With Mandolin (1870 to 1875), National Gallery of Art, Washington, DC [1].
• Skin abnormalities in the National Portrait Gallery [2].
• Clinical Gallery. Manifestations of neonatal herpes and herpetic cervicitis [3].

High impact information on X-Pand

• Inhibition of cellulose synthesis by isoxaben promoted a net redistribution of GFP-KOR1 toward a homogeneous population of compartments, distinct from early endosomes, which were concentrated close to the plasma membrane facing the root surface [4].
• Nevertheless, suspension-cultured cells can be habituated to grow in high concentrations of isoxaben, and apparently compensate for the disruption of cellulose synthesis by the modulation of other cell wall components [5].
• No growth acceleration, only slow growth, was observed in the cellulose synthase mutant cesA6(prc1-1) or in seedlings, which had been treated with the cellulose synthesis inhibitor isoxaben [6].
• The cellulose biosynthesis inhibitors 2,6-dichlorobenzonitrile and isoxaben both caused dramatic reductions in the number of cells depositing wall ingrowths, altered wall ingrowth morphology and visibly disrupted microfibril structure [7].
• Following isoxaben treatment, the radial array of microtubules persists beneath the plasma membrane of nonswollen tips, while this array is specifically disrupted in swollen tips [8].

Biological context of X-Pand

• Neurology in the National Gallery [9].

Anatomical context of X-Pand

• Disruption of cellulose synthesis by isoxaben causes tip swelling and disorganizes cortical microtubules in elongating conifer pollen tubes [8].

Associations of X-Pand with other chemical compounds

• The repeated isoxaben treatments applied in the past thus enhanced the isoxaben soil biodegradation; diuron, simazine, and paraquat had no influence on this rate enhancement [10].

Gene context of X-Pand

• Resistance against herbicide isoxaben and cellulose deficiency caused by distinct mutations in same cellulose synthase isoform CESA6 [11].
• EGC-1 included many novel initiatives in the glycosciences including electronic posters and papers, a Virtual Conference Centre, a Web-based hyperglossary, Virtual Trade and Employment Centres, refereed electronic publishing, and the creation of a Virtual Reality Gallery [12].
• There were 152 entries for the Medical Arts Society's annual exhibition and all were shown at the Westminster Gallery, London on October 14-19, last year [13].

Analytical, diagnostic and therapeutic context of X-Pand

• The Jech Gallery: an environmental face lift: the Dings Home-Zone project [14].
• Pesticide mobility in soils: assessment of the movement of isoxaben by soil thin-layer chromatography [15].

References