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Chemical Compound Review

Carsoron     2,6-dichlorobenzonitrile

Synonyms: Cyclomec, Decabane, Dyclomec, Casaron, Casoron, ...
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Disease relevance of Casoron gsr


High impact information on Casoron gsr


Chemical compound and disease context of Casoron gsr


Biological context of Casoron gsr


Anatomical context of Casoron gsr

  • These observations, coupled with the known profile of metabolites for dichlobenil, suggest that systemically-administered compounds causing site-specific lesions in the epithelium lining the DMM of the nasal cavity may do so by the in situ production of reactive epoxide metabolites which are then poorly capable of being detoxified [18].
  • Physiological and histological recovery of the olfactory mucosa of the frog after a dichlobenil injection [19].
  • In homogenates of the olfactory mucosa (mouse 1000 x g supernatants; rat microsomes), dichlobenil was metabolized and covalently bound to protein [20].
  • The NP-hydroxylation in olfactory microsomes was > 6 times higher than that in liver microsomes and was markedly decreased following addition of dichlobenil, DEDTC or metyrapone [16].

Associations of Casoron gsr with other chemical compounds


Gene context of Casoron gsr


Analytical, diagnostic and therapeutic context of Casoron gsr


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