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Chemical Compound Review:

HMDB13305 trimethyl-(2- propanoyloxyethyl)azanium

Synonyms: ZINC01736021, AR-1I7300, AC1L2P57, AC1Q65Q7, Propionylcholine, ...

O'Regan, S. et al., Kobzar, G.T. et al., Bishop, M.R. et al., King, J.A. et al., Kosh, J.W. et al.

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High impact information on Propionylcholine iodide

Is propionylcholine present in or synthesized by electric organ [1]?
1. Acetylcholine, bethanechol, carbachol and propionylcholine were all agonists of normal human detrusor smooth muscle [2].
The cooling of the water in the experimental bath results in an increase in the muscle contractions caused by muscarinomimetics while the responses to nicotinomimetic propionylcholine do not change [3].
Both of these analogues were incorporated into synaptic vesicles, but while butyrylcholine was as releasable as acetylcholine, propionylcholine was less releasable [4].
Identification of acetylcholine and propionylcholine in bull spermatozoa by integrated pyrolysis, gas chromatography and mass spectrometry [5].

Associations of Propionylcholine iodide with other chemical compounds

Finally, the synthesis, storage and release of analogues of acetylcholine with altered acetyl moieties, propionylcholine and butyrylcholine, were studied using the Torpedo electric organ [4].

References

Is propionylcholine present in or synthesized by electric organ? Kosh, J.W., Whittaker, V.P. J. Neurochem. (1985) [Pubmed]
Effect of choline ester analogues, noradrenaline and nifedipine on normal and hypertrophied human urinary bladder detrusor muscle. King, J.A., Huddart, H., Staff, W.G. Gen. Pharmacol. (1998) [Pubmed]
The muscle chemoreceptors of the ascidian Halocynthia aurantium. Kobzar, G.T., Shelkovnikov, S.A. Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. (1985) [Pubmed]
Studies on presynaptic cholinergic mechanisms using analogues of choline and acetate. O'Regan, S., Collier, B., Israel, M. J. Physiol. (Paris) (1982) [Pubmed]
Identification of acetylcholine and propionylcholine in bull spermatozoa by integrated pyrolysis, gas chromatography and mass spectrometry. Bishop, M.R., Sastry, B.V., Stavinoha, W.B. Biochim. Biophys. Acta (1977) [Pubmed]

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