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Chemical Compound Review:

SureCN50085 2-methoxy-6-methyl-phenol

Synonyms: NSC-7374, AG-E-93923, NSC7374, FR-1146, AC1L2NNF, ...

Imbus, H.R. et al., Kieć-Swierczyńska, M. et al., Kanerva, L. et al., Tarvainen, K. et al., Downs, A.M. et al., et al.

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Disease relevance of NSC7374

Palmoplantar dermatitis may be due to phenol-formaldehyde resin contact dermatitis [1].
Irritant dermatitis from phenol-formaldehyde resin powder [2].
Allergic dermatoses were due to natural rubber (latex) (4 cases) in protective gloves, phenol-formaldehyde resin (1 case) and cobalt naphthenate (1 case) [3].
Dermatitis was found in every fourth subject examined, oil acne in every tenth subject; 7.3% of the subjects examined were found to be allergy-positive to nickel, 6.9% to chromium, 5.0% to cobalt, 3.1% to formaldehyde, 1.5% to phenol-formaldehyde resin, 0% to phenol [4].

High impact information on NSC7374

The patient also had allergic patch test reactions to formaldehyde, phenol-formaldehyde resin, fragrance mix, and lauryl monoethanolamide, possibly from occupational exposure [5].

Analytical, diagnostic and therapeutic context of NSC7374

In order to determine whether phenol-formaldehyde-resin-coated wood particles would cause an acute decline in pulmonary function, 176 workers in 2 oriented strandboard production plants were given respiratory questionnaires and pulmonary function tests before and during their work shifts [6].

References

Palmoplantar dermatitis may be due to phenol-formaldehyde resin contact dermatitis. Downs, A.M., Sansom, J.E. Contact Derm. (1998) [Pubmed]
Irritant dermatitis from phenol-formaldehyde resin powder. Fregert, S. Contact Derm. (1980) [Pubmed]
Exposure, skin protection and occupational skin diseases in the glass-fibre-reinforced plastics industry. Tarvainen, K., Jolanki, R., Forsman-Grönholm, L., Estlander, T., Pfäffli, P., Juntunen, J., Kanerva, L. Contact Derm. (1993) [Pubmed]
The effect of the working environment on occupational skin disease development in workers processing rockwool. Kieć-Swierczyńska, M., Szymczk, W. International journal of occupational medicine and environmental health. (1995) [Pubmed]
Dentist's occupational allergic contact dermatitis caused by coconut diethanolamide, N-ethyl-4-toluene sulfonamide and 4-tolyldiethanolamine. Kanerva, L., Jolanki, R., Estlander, T. Acta Derm. Venereol. (1993) [Pubmed]
Acute effect upon pulmonary function of low level exposure to phenol-formaldehyde-resin-coated wood. Imbus, H.R., Tochilin, S.J. American Industrial Hygiene Association journal. (1988) [Pubmed]

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