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MeSH Review

Respiratory Function Tests

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Disease relevance of Respiratory Function Tests


Psychiatry related information on Respiratory Function Tests


High impact information on Respiratory Function Tests


Chemical compound and disease context of Respiratory Function Tests


Biological context of Respiratory Function Tests


Anatomical context of Respiratory Function Tests


Associations of Respiratory Function Tests with chemical compounds


Gene context of Respiratory Function Tests

  • Pulmonary function tests at 6 wk demonstrated increased lung volume in both p21(-/-) and p21(+/+) O(2) mice consistent with altered lung growth from neonatal exposure to hyperoxia [33].
  • Following several weeks of therapy, a gradual resolution of symptoms was noted, with normalization of pulmonary function test results and urine bFGF levels [34].
  • In the GSTM1 null genotype workers, there is a dose-response of lung function tests (FEV1, FEV1/FVC, MMEF) for ECH exposure, but not in the GSTM1 non-null genotype workers [35].
  • Similarly, there were no associations of any of the examined variants of the TNF genes with total IgE, specific IgE or pulmonary function tests in patients with allergic diseases [36].
  • In seven (88%) of these patients, changes in circulating VCAM-1 or E-selectin were associated with disease severity, falling with improvement in renal function or skin score, and rising with deterioration in pulmonary function tests [37].

Analytical, diagnostic and therapeutic context of Respiratory Function Tests


  1. Radiation-induced lung injury: a hypersensitivity pneumonitis? Gibson, P.G., Bryant, D.H., Morgan, G.W., Yeates, M., Fernandez, V., Penny, R., Breit, S.N. Ann. Intern. Med. (1988) [Pubmed]
  2. The effect of D-penicillamine on pulmonary findings in systemic sclerosis. Steen, V.D., Owens, G.R., Redmond, C., Rodnan, G.P., Medsger, T.A. Arthritis Rheum. (1985) [Pubmed]
  3. Amiodarone pulmonary toxicity: prospective evaluation of serial pulmonary function tests. Magro, S.A., Lawrence, E.C., Wheeler, S.H., Krafchek, J., Lin, H.T., Wyndham, C.R. J. Am. Coll. Cardiol. (1988) [Pubmed]
  4. Respiratory dysfunction due to L-dopa therapy for parkinsonism: diagnosis using serial pulmonary function tests and respiratory inductive plethysmography. Zupnick, H.M., Brown, L.K., Miller, A., Moros, D.A. Am. J. Med. (1990) [Pubmed]
  5. A prospective evaluation emphasizing pulmonary involvement in patients with mixed connective tissue disease. Sullivan, W.D., Hurst, D.J., Harmon, C.E., Esther, J.H., Agia, G.A., Maltby, J.D., Lillard, S.B., Held, C.N., Wolfe, J.F., Sunderrajan, E.V. Medicine (Baltimore) (1984) [Pubmed]
  6. Iloprost as cyclic five-day infusions in the treatment of scleroderma. An open pilot study in 20 patients treated for one year. Biasi, D., Carletto, A., Caramaschi, P., Zeminian, S., Pacor, M.L., Corrocher, R., Bambara, L.M. Revue du rhumatisme (English ed.) (1998) [Pubmed]
  7. Pulmonary status of habitual cocaine smokers. Tashkin, D.P., Khalsa, M.E., Gorelick, D., Chang, P., Simmons, M.S., Coulson, A.H., Gong, H. Am. Rev. Respir. Dis. (1992) [Pubmed]
  8. Routine pulmonary function tests during bleomycin therapy. Tests may be ineffective and potentially misleading. Lewis, B.M., Izbicki, R. JAMA (1980) [Pubmed]
  9. Complexity of terminal airspace geometry assessed by lung computed tomography in normal subjects and patients with chronic obstructive pulmonary disease. Mishima, M., Hirai, T., Itoh, H., Nakano, Y., Sakai, H., Muro, S., Nishimura, K., Oku, Y., Chin, K., Ohi, M., Nakamura, T., Bates, J.H., Alencar, A.M., Suki, B. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
  10. Pulmonary toxicity with combined modality therapy for limited stage small-cell lung cancer. Brooks, B.J., Seifter, E.J., Walsh, T.E., Lichter, A.S., Bunn, P.A., Zabell, A., Johnston-Early, A., Edison, M., Makuch, R.W., Cohen, M.H. J. Clin. Oncol. (1986) [Pubmed]
  11. Increased CD4+ T cell infiltrates in rheumatoid arthritis-associated interstitial pneumonitis compared with idiopathic interstitial pneumonitis. Turesson, C., Matteson, E.L., Colby, T.V., Vuk-Pavlovic, Z., Vassallo, R., Weyand, C.M., Tazelaar, H.D., Limper, A.H. Arthritis Rheum. (2005) [Pubmed]
  12. Rheumatoid arthritis lung disease. Determinants of radiographic and physiologic abnormalities. Saag, K.G., Kolluri, S., Koehnke, R.K., Georgou, T.A., Rachow, J.W., Hunninghake, G.W., Schwartz, D.A. Arthritis Rheum. (1996) [Pubmed]
  13. Phosphorus trichloride toxicity. Preliminary report. Wason, S., Gomolin, I., Gross, P., Mariam, S., Lovejoy, F.H. Am. J. Med. (1984) [Pubmed]
  14. Fatty acid levels and risk of asthma in young adults. Woods, R.K., Raven, J.M., Walters, E.H., Abramson, M.J., Thien, F.C. Thorax (2004) [Pubmed]
  15. Degradation of porstaglandin F2alpha in the human pulmonary circulation. Jose, P., Niederhauser, U., Piper, P.J., Robinson, C., Smith, A.P. Thorax (1976) [Pubmed]
  16. Evaluation of interstitial lung disease in mixed connective tissue disease (MCTD). Bodolay, E., Szekanecz, Z., Dévényi, K., Galuska, L., Csípo, I., Vègh, J., Garai, I., Szegedi, G. Rheumatology (Oxford, England) (2005) [Pubmed]
  17. Low levels of high density lipoprotein cholesterol in patients with active sarcoidosis. Salazar, A., Maña, J., Pinto, X., Argimon, J.M., Castiñeiras, M.J., Fiol, C., Pujol, R. Atherosclerosis (1998) [Pubmed]
  18. Lung structure and function in cigarette smokers. Hogg, J.C., Wright, J.L., Wiggs, B.R., Coxson, H.O., Opazo Saez, A., Paré, P.D. Thorax (1994) [Pubmed]
  19. Chronic cough in children: a manifestation of airway hyperreactivity. Cloutier, M.M., Loughlin, G.M. Pediatrics (1981) [Pubmed]
  20. Effectiveness of dexamethasone in preventing extubation failure in preterm infants at increased risk for airway edema. Couser, R.J., Ferrara, T.B., Falde, B., Johnson, K., Schilling, C.G., Hoekstra, R.E. J. Pediatr. (1992) [Pubmed]
  21. Albuterol responsiveness in infants with respiratory failure caused by respiratory syncytial virus infection. Hammer, J., Numa, A., Newth, C.J. J. Pediatr. (1995) [Pubmed]
  22. Eosinophils and eosinophil-derived proteins in children with moderate asthma. Hoekstra, M.O., Hovenga, H., Gerritsen, J., Kauffman, H.F. Eur. Respir. J. (1996) [Pubmed]
  23. Clinical, functional, and immunologic effects of sublingual immunotherapy in birch pollinosis: a 3-year randomized controlled study. Marogna, M., Spadolini, I., Massolo, A., Canonica, G.W., Passalacqua, G. J. Allergy Clin. Immunol. (2005) [Pubmed]
  24. A follow-up study of pulmonary function tests, bronchoalveolar lavage cells, and humoral and cellular immunity in bird fancier's lung. Yoshizawa, Y., Miyake, S., Sumi, Y., Hisauchi, K., Sato, T., Kurup, V.P. J. Allergy Clin. Immunol. (1995) [Pubmed]
  25. Reduced epithelial expression of secretory component in small airways correlates with airflow obstruction in chronic obstructive pulmonary disease. Pilette, C., Godding, V., Kiss, R., Delos, M., Verbeken, E., Decaestecker, C., De Paepe, K., Vaerman, J.P., Decramer, M., Sibille, Y. Am. J. Respir. Crit. Care Med. (2001) [Pubmed]
  26. Inflammatory cell profiles and T-lymphocyte subsets in chronic obstructive pulmonary disease and severe persistent asthma. Tsoumakidou, M., Tzanakis, N., Kyriakou, D., Chrysofakis, G., Siafakas, N.M. Clin. Exp. Allergy (2004) [Pubmed]
  27. Investigation of the chronic pulmonary effects of low-dose oral methotrexate in patients with rheumatoid arthritis: a prospective study incorporating HRCT scanning and pulmonary function tests. Dawson, J.K., Graham, D.R., Desmond, J., Fewins, H.E., Lynch, M.P. Rheumatology (Oxford, England) (2002) [Pubmed]
  28. Acquired immunodeficiency syndrome associated with blood-product transfusions. Jett, J.R., Kuritsky, J.N., Katzmann, J.A., Homburger, H.A. Ann. Intern. Med. (1983) [Pubmed]
  29. Carbon monoxide diffusing capacity is a poor predictor of clinically significant bleomycin lung. New Zealand Clinical Oncology Group. McKeage, M.J., Evans, B.D., Atkinson, C., Perez, D., Forgeson, G.V., Dady, P.J. J. Clin. Oncol. (1990) [Pubmed]
  30. D-penicillamine therapy and interstitial lung disease in scleroderma. A long-term followup study. de Clerck, L.S., Dequeker, J., Francx, L., Demedts, M. Arthritis Rheum. (1987) [Pubmed]
  31. Prazosin in hypertensive patients with chronic bronchitis and asthma: a brief report. Chodosh, S., Tuck, J., Pizzuto, D. Am. J. Med. (1989) [Pubmed]
  32. Selective low-level leg muscle training alleviates dyspnea in patients with heart failure. Beniaminovitz, A., Lang, C.C., LaManca, J., Mancini, D.M. J. Am. Coll. Cardiol. (2002) [Pubmed]
  33. The effect of neonatal hyperoxia on the lung of p21Waf1/Cip1/Sdi1-deficient mice. McGrath-Morrow, S.A., Cho, C., Soutiere, S., Mitzner, W., Tuder, R. Am. J. Respir. Cell Mol. Biol. (2004) [Pubmed]
  34. Pulmonary capillary hemangiomatosis with atypical endotheliomatosis: successful antiangiogenic therapy with doxycycline. Ginns, L.C., Roberts, D.H., Mark, E.J., Brusch, J.L., Marler, J.J. Chest (2003) [Pubmed]
  35. Decreased lung function associated with occupational exposure to epichlorohydrin and the modification effects of glutathione s-transferase polymorphisms. Luo, J.C., Cheng, T.J., Kuo, H.W., Chang, M.J. J. Occup. Environ. Med. (2004) [Pubmed]
  36. Lack of association between atopic asthma and the tumor necrosis factor alpha-308 gene polymorphism in a Czech population. Bucková, D., Hollá, L.I., Vasků, A., Znojil, V., Vácha, J. Journal of investigational allergology & clinical immunology : official organ of the International Association of Asthmology (INTERASMA) and Sociedad Latinoamericana de Alergia e Inmunología. (2002) [Pubmed]
  37. Serial circulating adhesion molecule levels reflect disease severity in systemic sclerosis. Denton, C.P., Bickerstaff, M.C., Shiwen, X., Carulli, M.T., Haskard, D.O., Dubois, R.M., Black, C.M. Br. J. Rheumatol. (1995) [Pubmed]
  38. The electrocardiogram in systemic sclerosis (scleroderma). Study of 102 consecutive cases with functional correlations and review of the literature. Follansbee, W.P., Curtiss, E.I., Rahko, P.S., Medsger, T.A., Lavine, S.J., Owens, G.R., Steen, V.D. Am. J. Med. (1985) [Pubmed]
  39. Clinical features of individuals with PI*SZ phenotype of alpha 1-antitrypsin deficiency. alpha 1-Antitrypsin Deficiency Registry Study Group. Turino, G.M., Barker, A.F., Brantly, M.L., Cohen, A.B., Connelly, R.P., Crystal, R.G., Eden, E., Schluchter, M.D., Stoller, J.K. Am. J. Respir. Crit. Care Med. (1996) [Pubmed]
  40. Long-term oral bronchodilator therapy of asthma with pirbuterol. Burki, N.K., Diamond, L. Clin. Pharmacol. Ther. (1978) [Pubmed]
  41. Late cardiopulmonary toxicity after treatment for Hodgkin's disease. Allavena, C., Conroy, T., Aletti, P., Bey, P., Lederlin, P. Br. J. Cancer (1992) [Pubmed]
  42. Predictors of perioperative morbidity and mortality in lung volume reduction surgery. Glaspole, I.N., Gabbay, E., Smith, J.A., Rabinov, M., Snell, G.I. Ann. Thorac. Surg. (2000) [Pubmed]
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