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Chemical Compound Review

Akaritox     1,2,4-trichloro-5-(4- chlorophenyl)sulfonyl...

Synonyms: Childion, Roztozol, Aredion, Dorvert, Roztoczol, ...
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Disease relevance of Childion


Psychiatry related information on Childion


High impact information on Childion

  • This study compared the relative effectiveness of a standard pancreatic enzyme supplement ('Creon', Duphar) and a new preparation ('Pancrease HL', Cilag) containing about 3 times the lipase and more than 5 times the protease activity [3].
  • On metabolic activation with rat liver microsomal S-9 enzymes, Chlordane, Dicofol and Tetradifon induced SCE frequency was higher than that of nonactivated cultures [4].
  • We present the findings of a pilot study which investigated the action of a commercial preparation of cerium nitrate/silver sulphadiazine mixture (Flammacerium, Duphar B. V. Holland) on 20 patients considered unsuitable for surgery [5].

Analytical, diagnostic and therapeutic context of Childion

  • The vaccine (Kavak iHL; Duphar) was tested in several vaccination programmes both alone and in combination with freeze dried measles (M) or distemper (D) vaccines [6].
  • In a first experiment, three generations (F0, F1, and F3) of the daphnids were exposed to sublethal levels of tetradifon (0.1, 0.18, 0.22, and 0.44 mg/l) and the effect of the toxicant on filtration and ingestion rates was determined [2].


  1. Surgical treatment of idiopathic hypertrophic subaortic stenosis (IHSS). Postoperative results in 30 patients following ventricular septal myotomy and myectomy (Morrow procedure). Reis, R.L., Hannah, H., Carley, J.E., Pugh, D.M. Circulation (1977) [Pubmed]
  2. Daphnia magna feeding behavior after exposure to tetradifon and recovery from intoxication. Villarroel, M.J., Ferrando, M.D., Sancho, E., Andreu, E. Ecotoxicol. Environ. Saf. (1999) [Pubmed]
  3. Comparison between a standard pancreatic supplement and a high enzyme preparation in cystic fibrosis. Morrison, G., Morrison, J.M., Redmond, A.O., Byers, C.A., McCracken, K.J., Dodge, J.A., Guilford, S.A., Bowden, M.W. Aliment. Pharmacol. Ther. (1992) [Pubmed]
  4. Cytokinetic and cytogenetic effect of agricultural chemicals on human lymphoid cells in vitro. II. Organochlorine pesticides. Sobti, R.C., Krishan, A., Davies, J. Arch. Toxicol. (1983) [Pubmed]
  5. The use of cerium nitrate-silver sulphadiazine as a topical burns dressing. Ross, D.A., Phipps, A.J., Clarke, J.A. British journal of plastic surgery. (1993) [Pubmed]
  6. Experiements with an inactivated hepatitis leptospirosis vaccine in vaccination programmes for dogs. Wilson, J.H., Hermann-Dekkers, W.M., Leemans-Dessy, S., Meijer, J.W. Vet. Rec. (1977) [Pubmed]
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