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Chemical Compound Review:

ACMC-1CG6Z 1,2,4-trimethylcyclohexane

Synonyms: AG-E-63240, ANW-41909, NSC-18907, KST-1B8709, NSC18907, ...

Myhre, O. et al., Zahlsen, K. et al., Myhre, O. et al.

Myhre, Vestad, Sagstuen, Aarnes, Fonnum, Myhre, Sterri, Bogen, Fonnum,

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High impact information on NSC18907

Here, we found that 1,2,4-trimethylcyclohexane induced a time and concentration dependent dephosphorylation of Akt-1 at Ser-473 and Raf-1 at Ser-259 [1].
Effects of the solvent 1,2,4-trimethylcyclohexane on respiratory burst in human neutrophil granulocytes. A chemiluminescence and electron paramagnetic resonance spectrometry study [2].
Accumulation and distribution of aliphatic (n-nonane), aromatic (1,2,4-trimethylbenzene) and naphthenic (1,2,4-trimethylcyclohexane) hydrocarbons in the rat after repeated inhalation [3].

Biological context of NSC18907

Erk1/2 phosphorylation and reactive oxygen species formation via nitric oxide and Akt-1/Raf-1 crosstalk in cultured rat cerebellar granule cells exposed to the organic solvent 1,2,4-trimethylcyclohexane [1].

References

Erk1/2 phosphorylation and reactive oxygen species formation via nitric oxide and Akt-1/Raf-1 crosstalk in cultured rat cerebellar granule cells exposed to the organic solvent 1,2,4-trimethylcyclohexane. Myhre, O., Sterri, S.H., Bogen, I.L., Fonnum, F. Toxicol. Sci. (2004) [Pubmed]
Effects of the solvent 1,2,4-trimethylcyclohexane on respiratory burst in human neutrophil granulocytes. A chemiluminescence and electron paramagnetic resonance spectrometry study. Myhre, O., Vestad, T.A., Sagstuen, E., Aarnes, H., Fonnum, F. Ann. N. Y. Acad. Sci. (1999) [Pubmed]
Accumulation and distribution of aliphatic (n-nonane), aromatic (1,2,4-trimethylbenzene) and naphthenic (1,2,4-trimethylcyclohexane) hydrocarbons in the rat after repeated inhalation. Zahlsen, K., Nilsen, A.M., Eide, I., Nilsen, O.G. Pharmacol. Toxicol. (1990) [Pubmed]

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