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Chemical Compound Review

NONANE     nonane

Synonyms: OyEEIe, nonan, n-Nonane, Shellsol 140, Nonyl hydride, ...
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Disease relevance of nonane


High impact information on nonane


Chemical compound and disease context of nonane


Biological context of nonane


Anatomical context of nonane


Associations of nonane with other chemical compounds


Gene context of nonane

  • Likewise, nonane significantly increased the expression of IL-1alpha, TNF-alpha and MCP-1 in skin and blood as compared to control at different time points [17].
  • The release of cytokines by nonane exposure was further supported by activation of NFkappaB p65 and corresponding degradation of IkappaBalpha in the skin [17].
  • The delta tolC mutant was more sensitive to nonane than the delta acrAB mutant [3].
  • The response of evidential breath alcohol testing instruments with subjects exposed to organic solvents and gases. II. White spirit and nonane [18].

Analytical, diagnostic and therapeutic context of nonane

  • 5. Analysis of the metabolites extracted from the microsomal incubations by gas chromatography/mass spectroscopy indicated that the parent isomers had been hydroxylated in the C-8 position on the nonane chain to give 2-(4-hydroxyphenyl)-8-hydroxynonane, 3-(4-hydroxyphenyl)-8-hydroxynonane and 4-(4-hydroxyphenyl)-8-hydroxynonane [19].


  1. Petroleum hydrocarbon toxicity studies XVII. Animal response to n-nonane vapor. Carpenter, C.P., Geary, D.L., Myers, R.C., Nachreiner, D.J., Sullivan, L.J., King, J.M. Toxicol. Appl. Pharmacol. (1978) [Pubmed]
  2. Percutaneous absorption and skin irritation upon low-level prolonged dermal exposure to nonane, dodecane and tetradecane in hairless rats. Babu, R.J., Chatterjee, A., Ahaghotu, E., Singh, M. Toxicology and industrial health. (2004) [Pubmed]
  3. Entry into and release of solvents by Escherichia coli in an organic-aqueous two-liquid-phase system and substrate specificity of the AcrAB-TolC solvent-extruding pump. Tsukagoshi, N., Aono, R. J. Bacteriol. (2000) [Pubmed]
  4. Degenerate Electron Exchange Reaction of n-Alkane Radical Cations in Solution. Borovkov, V.I., Gritsan, N.P., Yeletskikh, I.V., Bagryansky, V.A., Molin, Y.N. The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment & general theory (2006) [Pubmed]
  5. The effects of aliphatic (n-nonane), naphtenic (1,2, 4-trimethylcyclohexane), and aromatic (1,2,4-trimethylbenzene) hydrocarbons on respiratory burst in human neutrophil granulocytes. Myhre, O., Vestad, T.A., Sagstuen, E., Aarnes, H., Fonnum, F. Toxicol. Appl. Pharmacol. (2000) [Pubmed]
  6. Structural requirements of para-alkylphenols to bind to estrogen receptor. Tabira, Y., Nakai, M., Asai, D., Yakabe, Y., Tahara, Y., Shinmyozu, T., Noguchi, M., Takatsuki, M., Shimohigashi, Y. Eur. J. Biochem. (1999) [Pubmed]
  7. The metabolism of nonane, a JP-8 jet fuel component, by human liver microsomes, P450 isoforms and alcohol dehydrogenase and inhibition of human P450 isoforms by JP-8. Edwards, J.E., Rose, R.L., Hodgson, E. Chem. Biol. Interact. (2005) [Pubmed]
  8. Biochemical studies on the toxicity of n-octane and n-nonane. Khan, S., Pandya, K.P. Environmental research. (1980) [Pubmed]
  9. n-Octane and n-nonane induced alterations in xenobiotic metabolising enzyme activities and lipid peroxidation of rat liver. Khan, S., Mukhtar, H., Pandya, K.P. Toxicology (1980) [Pubmed]
  10. Inhalation experiments with mixtures of hydrocarbons. Experimental design, statistics and interpretation of kinetics and possible interactions. Eide, I., Zahlsen, K. Arch. Toxicol. (1996) [Pubmed]
  11. Percutaneous absorption and skin irritation of JP-8 (jet fuel). Kanikkannan, N., Patel, R., Jackson, T., Shaik, M.S., Singh, M. Toxicology (2001) [Pubmed]
  12. Homogeneous nucleation of n-nonane and n-propanol mixtures: a comparison of classical nucleation theory and experiments. Gaman, A.I., Napari, I., Winkler, P.M., Vehkamäki, H., Wagner, P.E., Strey, R., Viisanen, Y., Kulmala, M. The Journal of chemical physics. (2005) [Pubmed]
  13. Oleyl oleate synthesis by immobilized lipase from Candida sp.1619. Zhang, J., Xu, J. Chin. J. Biotechnol. (1995) [Pubmed]
  14. The cytotoxicity of volatile JP-8 jet fuel components in keratinocytes. Rogers, J.V., Siegel, G.L., Pollard, D.L., Rooney, A.D., McDougal, J.N. Toxicology (2004) [Pubmed]
  15. Occurrence of skin alkaloids in non-dendrobatid frogs from Brazil (Bufonidae), Australia (Myobatrachidae) and Madagascar (Mantellinae). Daly, J.W., Highet, R.J., Myers, C.W. Toxicon (1984) [Pubmed]
  16. The metabolism of n-nonane in male Fischer 344 rats. Serve, M.P., Bombick, D.D., Baughman, T.M., Jarnot, B.M., Ketcha, M., Mattie, D.R. Chemosphere (1995) [Pubmed]
  17. Assessment of skin irritation and molecular responses in rat skin exposed to nonane, dodecane and tetradecane. Babu, R.J., Chatterjee, A., Singh, M. Toxicol. Lett. (2004) [Pubmed]
  18. The response of evidential breath alcohol testing instruments with subjects exposed to organic solvents and gases. II. White spirit and nonane. Gill, R., Warner, H.E., Broster, C.G., Osselton, M.D., Ramsey, J.D., Wilson, H.K., Wilcox, A.H. Medicine, science, and the law. (1991) [Pubmed]
  19. Metabolism of several 14C-nonylphenol isomers by rainbow trout (Oncorhynchus mykiss): in vivo and in vitro microsomal metabolites. Meldahl, A.C., Nithipatikom, K., Lech, J.J. Xenobiotica (1996) [Pubmed]
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