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Chemical Compound Review

ALLYLBENZENE     prop-2-enylbenzene

Synonyms: allyl-benzene, Allyl benzene, AGN-PC-0052H8, CHEMBL501879, A29402_ALDRICH, ...
 
 
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Disease relevance of allylbenzene

  • A Bacillus megaterium strain was isolated from topsoil by a selective screening procedure with allylbenzene as a xenobiotic substrate [1].
  • It was concluded that both epoxide hydrolases and glutathione S-transferases can effectively detoxify the allylic epoxides derived from either allylbenzene or estragole and effectively prevent cellular or genetic toxicity of these reactive intermediates [2].
 

High impact information on allylbenzene

 

Biological context of allylbenzene

 

Anatomical context of allylbenzene

  • Similarly, incubation of allylbenzene epoxides with hepatic microsomal preparations and adult rat liver cell cultures gave rise to the formation of dihydrodiols [7].
 

Associations of allylbenzene with other chemical compounds

References

  1. Biocatalytic asymmetric hydroxylation of hydrocarbons with the topsoil-microorganism Bacillus megaterium. Adam, W., Lukacs, Z., Harmsen, D., Saha-Möller, C.R., Schreier, P. J. Org. Chem. (2000) [Pubmed]
  2. Metabolism of allylbenzene 2',3'-oxide and estragole 2',3'-oxide in the isolated perfused rat liver. Luo, G., Guenthner, T.M. J. Pharmacol. Exp. Ther. (1995) [Pubmed]
  3. A highly selective arene hydrogenation catalyst that operates in ionic liquid. Boxwell, C.J., Dyson, P.J., Ellis, D.J., Welton, T. J. Am. Chem. Soc. (2002) [Pubmed]
  4. Mechanism-based inactivation and reversibility: is there a new trend in the inactivation of cytochrome p450 enzymes? Blobaum, A.L. Drug Metab. Dispos. (2006) [Pubmed]
  5. Effect of in vitro exposure to styrene, styrene oxide, and other structurally related compounds on murine cell-mediated immunity. Grayson, M.H., Gill, S.S. Immunopharmacology (1986) [Pubmed]
  6. Relative ototoxicity of 21 aromatic solvents. Gagnaire, F., Langlais, C. Arch. Toxicol. (2005) [Pubmed]
  7. Biotransformation of allylbenzene analogues in vivo and in vitro through the epoxide-diol pathway. Delaforge, M., Janiaud, P., Levi, P., Morizot, J.P. Xenobiotica (1980) [Pubmed]
  8. Christmas gingerbread (Lebkuchen) and Christmas cheer--review of the potential role of mood elevating amphetamine-like compounds formed in vivo and in furno. Idle, J.R. Prague medical report. (2005) [Pubmed]
  9. Allylisopropylacetamide induces rat hepatic ornithine decarboxylase. Kitchin, K.T., Brown, J.L. J. Biochem. Toxicol. (1987) [Pubmed]
 
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