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Chemical Compound Review

Ethylbenzol     ethylbenzene

Synonyms: Ethylenzene, Etilbenzene, Etylobenzen, Aethylbenzol, ETHYLBENZENE, ...
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Disease relevance of ethylbenzene


Psychiatry related information on ethylbenzene


High impact information on ethylbenzene


Chemical compound and disease context of ethylbenzene


Biological context of ethylbenzene


Anatomical context of ethylbenzene


Associations of ethylbenzene with other chemical compounds


Gene context of ethylbenzene


Analytical, diagnostic and therapeutic context of ethylbenzene

  • Enzymatic ethylbenzene oxidation was stereospecific, with (S)-(-)-1-phenylethanol being the only enantiomer detected by chiral high-pressure liquid chromatography analysis [13].
  • Parallel characterization of anaerobic toluene- and ethylbenzene-degrading microbial consortia by PCR-denaturing gradient gel electrophoresis, RNA-DNA membrane hybridization, and DNA microarray technology [32].
  • The goal of this study was to examine the role of pituitary input on the modulation of CYP2C11 and CYP2B after treatment with the aromatic hydrocarbon ethylbenzene (EB) [33].
  • Rats were treated with a single intraperitoneal injection of ethylbenzene in corn oil and the effects on cytochrome P450 3A-dependent activities, immunoreactive protein levels and RNA levels were examined [34].
  • Gas chromatographic determination of benzene, toluene, ethylbenzene and xylenes using flame ionization detector in water samples with direct aqueous injection up to 250 microl [35].


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  2. Substrate-dependent regulation of anaerobic degradation pathways for toluene and ethylbenzene in a denitrifying bacterium, strain EbN1. Kühner, S., Wöhlbrand, L., Fritz, I., Wruck, W., Hultschig, C., Hufnagel, P., Kube, M., Reinhardt, R., Rabus, R. J. Bacteriol. (2005) [Pubmed]
  3. Development and characterization of a green fluorescent protein-based bacterial biosensor for bioavailable toluene and related compounds. Stiner, L., Halverson, L.J. Appl. Environ. Microbiol. (2002) [Pubmed]
  4. Multiple-subunit genes of the aromatic-ring-hydroxylating dioxygenase play an active role in biphenyl and polychlorinated biphenyl degradation in Rhodococcus sp. strain RHA1. Iwasaki, T., Miyauchi, K., Masai, E., Fukuda, M. Appl. Environ. Microbiol. (2006) [Pubmed]
  5. Microbial conversion of ethylbenzene to 1-phenethanol and acetophenone by Nocardia tartaricans ATCC 31190. Cox, D.P., Goldsmith, C.D. Appl. Environ. Microbiol. (1979) [Pubmed]
  6. Differential susceptibility of rats and guinea pigs to the ototoxic effects of ethyl benzene. Cappaert, N.L., Klis, S.F., Muijser, H., Kulig, B.M., Ravensberg, L.C., Smoorenburg, G.F. Neurotoxicology and teratology. (2002) [Pubmed]
  7. A GC-MS method for the detection of toluene and ethylbenzene in volatile substance abuse. El-Haj, B.M., Al-Amri, A.M., Hassan, M.H., Bin-Khadem, R.K., Al-Hadi, A.A. Journal of analytical toxicology. (2000) [Pubmed]
  8. Competition between hydrocarbon and barbiturate for spectral binding to hepatic cytochrome P-450. Inferences concerning spin state of the enzyme. Backes, W.L., Means, M., Canady, W.J. J. Biol. Chem. (1984) [Pubmed]
  9. Application of artificial neural networks and DFT-based parameters for prediction of reaction kinetics of ethylbenzene dehydrogenase. Szaleniec, M., Witko, M., Tadeusiewicz, R., Goclon, J. J. Comput. Aided Mol. Des. (2006) [Pubmed]
  10. Dynamics of an oligotrophic bacterial aquifer community during contact with a groundwater plume contaminated with benzene, toluene, ethylbenzene, and xylenes: an in situ mesocosm study. Hendrickx, B., Dejonghe, W., Boënne, W., Brennerova, M., Cernik, M., Lederer, T., Bucheli-Witschel, M., Bastiaens, L., Verstraete, W., Top, E.M., Diels, L., Springael, D. Appl. Environ. Microbiol. (2005) [Pubmed]
  11. Sensitive detection of a novel class of toluene-degrading denitrifiers, Azoarcus tolulyticus, with small-subunit rRNA primers and probes. Zhou, J., Palumbo, A.V., Tiedje, J.M. Appl. Environ. Microbiol. (1997) [Pubmed]
  12. Biodegradation of mixtures of substituted benzenes by Pseudomonas sp. strain JS150. Haigler, B.E., Pettigrew, C.A., Spain, J.C. Appl. Environ. Microbiol. (1992) [Pubmed]
  13. In vitro studies on the initial reactions of anaerobic ethylbenzene mineralization. Johnson, H.A., Spormann, A.M. J. Bacteriol. (1999) [Pubmed]
  14. Isolation and characterization of a thermotolerant bacterium Ralstonia sp. strain PHS1 that degrades benzene, toluene, ethylbenzene, and o-xylene. Lee, S.K., Lee, S.B. Appl. Microbiol. Biotechnol. (2001) [Pubmed]
  15. Developmental toxicities of ethylbenzene, ortho-, meta-, para-xylene and technical xylene in rats following inhalation exposure. Saillenfait, A.M., Gallissot, F., Morel, G., Bonnet, P. Food Chem. Toxicol. (2003) [Pubmed]
  16. Isolation and characterization of anaerobic ethylbenzene dehydrogenase, a novel Mo-Fe-S enzyme. Johnson, H.A., Pelletier, D.A., Spormann, A.M. J. Bacteriol. (2001) [Pubmed]
  17. Effect of organic solvents on the yield of solvent-tolerant Pseudomonas putida S12. Isken, S., Derks, A., Wolffs, P.F., de Bont, J.A. Appl. Environ. Microbiol. (1999) [Pubmed]
  18. Subtle difference between benzene and toluene dioxygenases of Pseudomonas putida. Bagnéris, C., Cammack, R., Mason, J.R. Appl. Environ. Microbiol. (2005) [Pubmed]
  19. Inhalation pharmacokinetics of ethylbenzene in B6C3F1 mice. Charest-Tardif, G., Tardif, R., Krishnan, K. Toxicol. Appl. Pharmacol. (2006) [Pubmed]
  20. Changes in the expression of cytochrome P450s 2B1, 2B2, 2E1, and 2C11 in response to daily aromatic hydrocarbon treatment. Bergeron, R.M., Desai, K., Serron, S.C., Cawley, G.F., Eyer, C.S., Backes, W.L. Toxicol. Appl. Pharmacol. (1999) [Pubmed]
  21. Hydrophobic-phase-modified fused-silica columns for capillary electrophoresis. Russo, M.V., Goretti, G. Journal of chromatography. A. (2000) [Pubmed]
  22. Effects of ethylbenzene, toluene, and xylene on the induction of micronuclei in bone marrow polychromatic erythrocytes of mice. Mohtashamipur, E., Norpoth, K., Woelke, U., Huber, P. Arch. Toxicol. (1985) [Pubmed]
  23. Metabolism of ethylbenzene by human liver microsomes and recombinant human cytochrome P450s (CYP). Sams, C., Loizou, G.D., Cocker, J., Lennard, M.S. Toxicol. Lett. (2004) [Pubmed]
  24. Simultaneous exposure to ethyl benzene and noise: synergistic effects on outer hair cells. Cappaert, N.L., Klis, S.F., Muijser, H., Kulig, B.M., Smoorenburg, G.F. Hear. Res. (2001) [Pubmed]
  25. Exposure to xylene and ethylbenzene. II. Concentration in subcutaneous adipose tissue. Engström, J., Bjurström, R. Scandinavian journal of work, environment & health. (1978) [Pubmed]
  26. Substrate interactions during the biodegradation of benzene, toluene, ethylbenzene, and xylene (BTEX) hydrocarbons by the fungus Cladophialophora sp. strain T1. Prenafeta-Boldú, F.X., Vervoort, J., Grotenhuis, J.T., Van Groenestijn, J.W. Appl. Environ. Microbiol. (2002) [Pubmed]
  27. Environmental exposure to volatile organic compounds among workers in Mexico City as assessed by personal monitors and blood concentrations. Romieu, I., Ramirez, M., Meneses, F., Ashley, D., Lemire, S., Colome, S., Fung, K., Hernandez-Avila, M. Environ. Health Perspect. (1999) [Pubmed]
  28. Three efflux pumps are required to provide efficient tolerance to toluene in Pseudomonas putida DOT-T1E. Rojas, A., Duque, E., Mosqueda, G., Golden, G., Hurtado, A., Ramos, J.L., Segura, A. J. Bacteriol. (2001) [Pubmed]
  29. Anaerobic degradation of ethylbenzene by a new type of marine sulfate-reducing bacterium. Kniemeyer, O., Fischer, T., Wilkes, H., Glöckner, F.O., Widdel, F. Appl. Environ. Microbiol. (2003) [Pubmed]
  30. Ethylbenzene-mediated induction of cytochrome P450 isozymes in male and female rats. Sequeira, D.J., Eyer, C.S., Cawley, G.F., Nick, T.G., Backes, W.L. Biochem. Pharmacol. (1992) [Pubmed]
  31. Initial reactions in anaerobic ethylbenzene oxidation by a denitrifying bacterium, strain EB1. Ball, H.A., Johnson, H.A., Reinhard, M., Spormann, A.M. J. Bacteriol. (1996) [Pubmed]
  32. Parallel characterization of anaerobic toluene- and ethylbenzene-degrading microbial consortia by PCR-denaturing gradient gel electrophoresis, RNA-DNA membrane hybridization, and DNA microarray technology. Koizumi, Y., Kelly, J.J., Nakagawa, T., Urakawa, H., El-Fantroussi, S., Al-Muzaini, S., Fukui, M., Urushigawa, Y., Stahl, D.A. Appl. Environ. Microbiol. (2002) [Pubmed]
  33. Effect of hypophysectomy and growth hormone replacement on the modulation of p450 expression after treatment with the aromatic hydrocarbon ethylbenzene. Serron, S.C., Zhang, S., Bergeron, R.M., Backes, W.L. Toxicol. Appl. Pharmacol. (2001) [Pubmed]
  34. Induction of P450 3A by ethylbenzene without altering RNA levels. Yuan, W., Cawley, G.F., Eyer, C.S., Backes, W.L. Biochem. Biophys. Res. Commun. (1994) [Pubmed]
  35. Gas chromatographic determination of benzene, toluene, ethylbenzene and xylenes using flame ionization detector in water samples with direct aqueous injection up to 250 microl. Kubinec, R., Adamuscin, J., Jurdáková, H., Foltin, M., Ostrovský, I., Kraus, A., Soják, L. Journal of chromatography. A. (2005) [Pubmed]
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