Gene Review:
SEC63 - SEC63 homolog (S. cerevisiae)
Homo sapiens
Synonyms:
DNAJC23, ERdj2, PRO2507, SEC63L, Translocation protein SEC63 homolog
- Mutations in SEC63 cause autosomal dominant polycystic liver disease. Davila, S., Furu, L., Gharavi, A.G., Tian, X., Onoe, T., Qian, Q., Li, A., Cai, Y., Kamath, P.S., King, B.F., Azurmendi, P.J., Tahvanainen, P., Kääriäinen, H., Höckerstedt, K., Devuyst, O., Pirson, Y., Martin, R.S., Lifton, R.P., Tahvanainen, E., Torres, V.E., Somlo, S. Nat. Genet. (2004)
- Homologs of the yeast Sec complex subunits Sec62p and Sec63p are abundant proteins in dog pancreas microsomes. Tyedmers, J., Lerner, M., Bies, C., Dudek, J., Skowronek, M.H., Haas, I.G., Heim, N., Nastainczyk, W., Volkmer, J., Zimmermann, R. Proc. Natl. Acad. Sci. U.S.A. (2000)
- The Brl domain in Sec63p is required for assembly of functional endoplasmic reticulum translocons. Jermy, A.J., Willer, M., Davis, E., Wilkinson, B.M., Stirling, C.J. J. Biol. Chem. (2006)
- Extensive mutational analysis of PRKCSH and SEC63 broadens the spectrum of polycystic liver disease. Waanders, E., te Morsche, R.H., de Man, R.A., Jansen, J.B., Drenth, J.P. Hum. Mutat. (2006)
- Human Sec63 endoplasmic reticulum membrane protein, map position 6q21. Woollatt, E., Pine, K.A., Shine, J., Sutherland, G.R., Iismaa, T.P. Chromosome Res. (1999)
- Mammalian Sec61 is associated with Sec62 and Sec63. Meyer, H.A., Grau, H., Kraft, R., Kostka, S., Prehn, S., Kalies, K.U., Hartmann, E. J. Biol. Chem. (2000)
- Relationship between calnexin and BiP in suppressing aggregation and promoting refolding of protein and glycoprotein substrates. Stronge, V.S., Saito, Y., Ihara, Y., Williams, D.B. J. Biol. Chem. (2001)
- Protein transport into the endoplasmic reticulum: mechanisms and pathologies. Zimmermann, R., M??ller, L., Wullich, B. Trends in molecular medicine (2006)