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Gene Review

envZ  -  osmolarity sensor protein EnvZ

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

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Disease relevance of envZ


High impact information on envZ

  • All four insertions were located in the ompR/envZ regulon [2].
  • The sequence data also showed that ompR and envZ form an operon, where the coding regions overlap by four base-pairs [3].
  • Analysis of ompR frameshift mutations showed that translation of envZ is almost totally dependent on the translation of the upstream gene ompR [3].
  • Mutations in envZ and ackA-pta, which disrupted two distinct sources of OmpR phosphorylation, indicated that SPI2 activation by chelators or a shift from rich to acidic minimal medium is largely dependent on functional EnvZ [4].

Biological context of envZ


Anatomical context of envZ


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