Gene Review:
VDAC1 - voltage-dependent anion channel 1
Homo sapiens
Synonyms:
MGC111064, Outer mitochondrial membrane protein porin 1, PORIN, Plasmalemmal porin, Porin 31HL, ...
Ram,
Cullinane,
Blom,
Gulati,
McQuillen,
Monks,
O'Connell,
Boden,
Elkins,
Pangburn,
Dahlbäck,
Rice,
Ayala,
Vasquez,
Wetzler,
So,
Hume,
Duan,
Collier,
Yamazaki,
Horowitz,
Hinsch,
De Pinto,
Aires,
Schneider,
Messina,
Hinsch,
Derrick,
Maiden,
Feavers,
van Putten,
Duensing,
Carlson,
Kotarsky,
Tabasum,
Mannisto,
Heikinheimo,
Hansson,
Fellman,
Pastorino,
Hoek,
Shulga,
Hinsch,
Asmarinah,
Hinsch,
Konrad,
- Changes of voltage-dependent anion-selective channel proteins VDAC1 and VDAC2 brain levels in patients with Alzheimer's disease and Down syndrome. Yoo, B.C., Fountoulakis, M., Cairns, N., Lubec, G. Electrophoresis (2001)
- Targeting of the pro-apoptotic VDAC-like porin (PorB) of Neisseria gonorrhoeae to mitochondria of infected cells. Müller, A., Günther, D., Brinkmann, V., Hurwitz, R., Meyer, T.F., Rudel, T. EMBO J. (2000)
- In vitro interactions between the two mitochondrial membrane proteins VDAC and cytochrome c oxidase. Roman, I., Figys, J., Steurs, G., Zizi, M. Biochemistry (2005)
- Mapping of the human Voltage-Dependent Anion Channel isoforms 1 and 2 reconsidered. Messina, A., Oliva, M., Rosato, C., Huizing, M., Ruitenbeek, W., van den Heuvel, L.P., Forte, M., Rocchi, M., De Pinto, V. Biochem. Biophys. Res. Commun. (1999)
- Proteomic identification of new biomarkers and application in thyroid cytology. Torres-Cabala, C., Bibbo, M., Panizo-Santos, A., Barazi, H., Krutzsch, H., Roberts, D.D., Merino, M.J. Acta Cytol. (2006)
- Anion transport in heart. Hume, J.R., Duan, D., Collier, M.L., Yamazaki, J., Horowitz, B. Physiol. Rev. (2000)
- Modulation of Neisseria porin (PorB) by cytosolic ATP/GTP of target cells: parallels between pathogen accommodation and mitochondrial endosymbiosis. Rudel, T., Schmid, A., Benz, R., Kolb, H.A., Lang, F., Meyer, T.F. Cell (1996)
- Binding of C4b-binding protein to porin: a molecular mechanism of serum resistance of Neisseria gonorrhoeae. Ram, S., Cullinane, M., Blom, A.M., Gulati, S., McQuillen, D.P., Monks, B.G., O'Connell, C., Boden, R., Elkins, C., Pangburn, M.K., Dahlbäck, B., Rice, P.A. J. Exp. Med. (2001)
- Gonococcal invasion of epithelial cells driven by P.IA, a bacterial ion channel with GTP binding properties. van Putten, J.P., Duensing, T.D., Carlson, J. J. Exp. Med. (1998)
- Complement component C3 fixes selectively to the major outer membrane protein (MOMP) of Legionella pneumophila and mediates phagocytosis of liposome-MOMP complexes by human monocytes. Bellinger-Kawahara, C., Horwitz, M.A. J. Exp. Med. (1990)
- A pharmacologic target of G3139 in melanoma cells may be the mitochondrial VDAC. Lai, J.C., Tan, W., Benimetskaya, L., Miller, P., Colombini, M., Stein, C.A. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Cisplatin preferentially binds mitochondrial DNA and voltage-dependent anion channel protein in the mitochondrial membrane of head and neck squamous cell carcinoma: possible role in apoptosis. Yang, Z., Schumaker, L.M., Egorin, M.J., Zuhowski, E.G., Guo, Z., Cullen, K.J. Clin. Cancer Res. (2006)
- Colocalization of BAX with BID and VDAC-1 in nimesulide-induced apoptosis of human colon adenocarcinoma COLO 205 cells. Godlewski, M.M., Gajkowska, B., Lamparska-Przybysz, M., Motyl, T. Anticancer Drugs (2002)
- Voltage-dependent anion channel (VDAC) as mitochondrial governator--thinking outside the box. Lemasters, J.J., Holmuhamedov, E. Biochim. Biophys. Acta (2006)
- Biphasic binding kinetics between FepA and its ligands. Payne, M.A., Igo, J.D., Cao, Z., Foster, S.B., Newton, S.M., Klebba, P.E. J. Biol. Chem. (1997)
- VDAC1 is a transplasma membrane NADH-ferricyanide reductase. Baker, M.A., Lane, D.J., Ly, J.D., De Pinto, V., Lawen, A. J. Biol. Chem. (2004)
- Human genes encoding the voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane: mapping and identification of two new isoforms. Blachly-Dyson, E., Baldini, A., Litt, M., McCabe, E.R., Forte, M. Genomics (1994)
- Characterization of VDAC1 as a plasma membrane NADH-oxidoreductase. Baker, M.A., Ly, J.D., Lawen, A. Biofactors (2004)
- The murine voltage-dependent anion channel gene family. Conserved structure and function. Sampson, M.J., Lovell, R.S., Craigen, W.J. J. Biol. Chem. (1997)
- The voltage-dependent anion channel-1 modulates apoptotic cell death. Zaid, H., Abu-Hamad, S., Israelson, A., Nathan, I., Shoshan-Barmatz, V. Cell Death Differ. (2005)
- Intracellular localization and isoform expression of the voltage-dependent anion channel (VDAC) in normal and dystrophic skeletal muscle. Massa, R., Marliera, L.N., Martorana, A., Cicconi, S., Pierucci, D., Giacomini, P., De Pinto, V., Castellani, L. J. Muscle Res. Cell. Motil. (2000)
- VDAC2 (porin-2) expression pattern and localization in the bovine testis. Hinsch, K.D., Asmarinah, n.u.l.l., Hinsch, E., Konrad, L. Biochim. Biophys. Acta (2001)
- Mitochondrial voltage-dependent anion channel is involved in dopamine-induced apoptosis. Premkumar, A., Simantov, R. J. Neurochem. (2002)
- Hexokinase II: the integration of energy metabolism and control of apoptosis. Pastorino, J.G., Hoek, J.B. Current medicinal chemistry. (2003)
- Porin interaction with hexokinase and glycerol kinase: metabolic microcompartmentation at the outer mitochondrial membrane. Adams, V., Griffin, L., Towbin, J., Gelb, B., Worley, K., McCabe, E.R. Biochem. Med. Metab. Biol. (1991)
- Identification of the hypoxia-inducible factor 1 alpha-responsive HGTD-P gene as a mediator in the mitochondrial apoptotic pathway. Lee, M.J., Kim, J.Y., Suk, K., Park, J.H. Mol. Cell. Biol. (2004)
- Functional interaction of endothelial nitric oxide synthase with a voltage-dependent anion channel. Sun, J., Liao, J.K. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Crystal structure of an Fab fragment in complex with a meningococcal serosubtype antigen and a protein G domain. Derrick, J.P., Maiden, M.C., Feavers, I.M. J. Mol. Biol. (1999)
- Activation of glycogen synthase kinase 3beta disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity. Pastorino, J.G., Hoek, J.B., Shulga, N. Cancer Res. (2005)
- In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death. Azoulay-Zohar, H., Israelson, A., Abu-Hamad, S., Shoshan-Barmatz, V. Biochem. J. (2004)
- Neisserial porin-induced dendritic cell activation is MyD88 and TLR2 dependent. Singleton, T.E., Massari, P., Wetzler, L.M. J. Immunol. (2005)
- Increased susceptibility to apoptosis in CD45(+) myeloma cells accompanied by the increased expression of VDAC1. Liu, S., Ishikawa, H., Tsuyama, N., Li, F.J., Abroun, S., Otsuyama, K.I., Zheng, X., Ma, Z., Maki, Y., Iqbal, M.S., Obata, M., Kawano, M.M. Oncogene (2006)
- BCS1L is expressed in critical regions for neural development during ontogenesis in mice. Kotarsky, H., Tabasum, I., Mannisto, S., Heikinheimo, M., Hansson, S., Fellman, V. Gene Expr. Patterns (2007)
- Neisseria gonorrhoeae porin P1.B induces endosome exocytosis and a redistribution of Lamp1 to the plasma membrane. Ayala, P., Vasquez, B., Wetzler, L., So, M. Infect. Immun. (2002)
- Voltage-dependent anion-selective channel (VDAC) interacts with the dynein light chain Tctex1 and the heat-shock protein PBP74. Schwarzer, C., Barnikol-Watanabe, S., Thinnes, F.P., Hilschmann, N. Int. J. Biochem. Cell Biol. (2002)
- New EMBO members' review: viral and bacterial proteins regulating apoptosis at the mitochondrial level. Boya, P., Roques, B., Kroemer, G. EMBO J. (2001)
- Voltage-dependent anion-selective channels VDAC2 and VDAC3 are abundant proteins in bovine outer dense fibers, a cytoskeletal component of the sperm flagellum. Hinsch, K.D., De Pinto, V., Aires, V.A., Schneider, X., Messina, A., Hinsch, E. J. Biol. Chem. (2004)
- Neisseria meningitidis porin PorB interacts with mitochondria and protects cells from apoptosis. Massari, P., Ho, Y., Wetzler, L.M. Proc. Natl. Acad. Sci. U.S.A. (2000)